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Sealing technology of plant capsule

A technology of plant capsules and plant sources, applied in the field of medicine, can solve problems such as reducing the chance of exposure, harm to the body, leakage of active ingredients, etc., and achieve the effect of improving sealing performance, widely used, and overcoming leakage

Inactive Publication Date: 2012-12-26
北京东兴堂科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But there are serious defects and deficiencies at the same time: First, the process of extracting gelatin from animal skin and bones needs to go through multiple chemical treatment steps. These chemical treatment processes will not only cause serious pollution to the environment, but also have certain impurities and heavy metals in the raw materials. , will cause harm to the body; second, gelatin is a high-protein substance that is easy to breed various bacteria, therefore, in the process of producing capsules, it must be sterilized, and the residues of these treatments have adverse effects on the human body; The reason is that the molecular structure of gelatin is unstable, and it is easily affected by temperature and humidity. It is difficult to guarantee halal, which hinders the use of such products in Islamic countries; fifth, gelatin disintegrates slowly, and the glycerin contained is not easy to digest, and the proportion of capsule shells is too large compared with effective drugs
However, the sealing performance of vegetable capsules is poor, and it is easy to cause leakage, volatilization, moisture regain or oxidative deterioration of the active ingredients in the capsules, which is not conducive to preservation.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Mix 10 parts by mass of carrageenan powder, 40 parts by mass of water, and 25 parts by mass of ethanol evenly, heat in a water bath to keep the temperature at about 50°C, and heat for about 30 hours to obtain a sealing bandage forming agent. ℃, and the relative humidity is about 50%, the sealing bandage forming agent is sprayed on the seams of the upper and lower capsules of the vegetable capsule.

Embodiment 2

[0018] Mix 15 parts by mass of carrageenan powder, 40 parts by mass of water, and 50 parts by mass of ethanol evenly, heat in a water bath to keep the temperature at about 55°C, and heat for about 26 hours to obtain a sealing bandage forming agent. ℃, and the relative humidity is about 50%, the sealing bandage forming agent is sprayed on the seams of the upper and lower capsules of the vegetable capsule.

Embodiment 3

[0020] Mix 18 parts by mass of carrageenan powder, 45 parts by mass of water, and 40 parts by mass of ethanol evenly, heat in a water bath to keep the temperature at about 50°C, and heat for about 24 hours to obtain a sealing bandage forming agent. ℃, and the relative humidity is about 50%, the sealing bandage forming agent is sprayed on the seams of the upper and lower capsules of the vegetable capsule.

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PUM

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Abstract

The invention belongs to the medical field, in particular to a sealing technology of a plant capsule. The plant capsule is divided into an upper capsule body and a lower capsule body which are in mutually inserting connection, and the inserting connection position of the upper capsule body and the lower capsule body is sealed by a sealing bandage which uses plant as a raw material. The sealing bandage is prepared by a sealing bandage formation agent which includes 10-30 parts by weight of carrageenan powder, 40-55 parts by weight of water and 25-50 parts by weight of ethanol. The technology increases the sealing performance of the plant capsule and effectively overcomes the defect that the effective ingredients in the plant capsule are not conducive to preservation due to leakage, evaporation, moisture regain or oxidation deterioration, and the plant capsule can widely used.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a plant capsule sealing technology. Background technique [0002] Capsules have been officially listed as pharmaceutical excipients by the state, and are also excipients and manifestations of pharmaceuticals. The main material of capsules currently used is animal-derived gelatin. Although the capsules produced by it have good strength and toughness, and are rich in 18 kinds of amino acids and various nutrients. But there are serious defects and deficiencies at the same time: First, the process of extracting gelatin from animal skin and bones needs to go through multiple chemical treatment steps. These chemical treatment processes will not only cause serious pollution to the environment, but also have certain impurities and heavy metals in the raw materials. , will cause harm to the body; second, gelatin is a high-protein substance that is easy to breed various bacteria, there...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61J3/07A61K47/36
Inventor 贾海坤贾海涛
Owner 北京东兴堂科技发展有限公司