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Compositions for reducing, ameliorating, treating, or preventing condition of dry eye and methods of making and using same

A composition and dry eye technology, applied in the field of treatment or prevention of dry eye composition, improvement, relief, can solve problems such as preservative discomfort

Inactive Publication Date: 2010-06-23
BAUSCH & LOMB INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, for sensitive patients, especially those who already suffer from dry eye, these preservatives may cause some discomfort

Method used

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  • Compositions for reducing, ameliorating, treating, or preventing condition of dry eye and methods of making and using same
  • Compositions for reducing, ameliorating, treating, or preventing condition of dry eye and methods of making and using same
  • Compositions for reducing, ameliorating, treating, or preventing condition of dry eye and methods of making and using same

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Embodiment Construction

[0026] In general, the present invention provides compositions capable of alleviating, ameliorating, treating or preventing the discomfort caused by dry eye.

[0027] In one aspect, the composition has a low risk of introducing undesired exogenous side effects such as undesired irritation, burning or stinging sensations. Alternatively, the composition is mild to the ocular surface.

[0028] In another aspect, the composition of the present invention comprises: (a) an alginate; and (b) a polyol, wherein the composition has a pH in the range of about 5 to about 7.5.

[0029] In another aspect, the composition of the present invention comprises: (a) alginate; (b) at least one polyol; and (c) a pharmaceutically acceptable carrier; wherein the pH of the composition is between about 5 and in the range of about 7.5. In one embodiment, the pH of the composition is in the range of about 5.5 to about 7.5. In another embodiment, the pH of the composition is from about 6 to about 7.5 (...

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Abstract

Compositions for relief, treatment, or prevention of a condition of dry eye comprise alginate, at least a polyol, and a pharmaceutically acceptable carrier, wherein the compositions have pH in the range from about 5 to about 7.5. In some embodiment, the compositions can further include a chelating agent, a buffering system or agent, an organic acid, or combinations thereof.

Description

technical field [0001] The present invention relates to a composition for alleviating, improving, treating or preventing dry eye and methods for preparing and using the composition. In particular, the present invention relates to compositions and methods for alleviating, ameliorating, treating or preventing the discomfort of dry eye. Background technique [0002] Dry eye, also known as keratoconjunctivitis sicca or dyslacrima, is a common ophthalmic disorder affecting millions of people. Patients with dry eye may experience burning, dryness and constant irritation. In severe cases, dry eye can severely impair a person's vision and thus impair the patient's activities such as driving. Certain diseases such as Xerosis (Sjogren's disease) show dry eye symptoms. In addition, as a person ages, the lacrimal glands of the eye produce less moisture, resulting in dry, red, itchy, and gritty eyes. [0003] Although it appears that dry eye may be caused by a variety of unrelated et...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/00A61K47/26A61K47/36
CPCA61K9/0048A61K47/26A61K47/36A61P27/02A61K31/734A61K47/10
Inventor 夏尔宁D·M·亚尼
Owner BAUSCH & LOMB INC