Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Novel compound antihypertensive drug

A technology for high blood pressure and compound preparations, applied in the field of medicine, can solve the problems of inaccurate clinical drug dosage, affect drug efficacy, increase side effects, etc., and achieve the effects of improving antihypertensive efficacy, fewer adverse reactions, and good antihypertensive effect.

Inactive Publication Date: 2010-06-30
JIANGSU JIBEIER PHARMA
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] The product of the present invention overcomes that when nitrendipine and metoprolol are used clinically, the drug dose is increased to ensure the curative effect when a single drug is used alone, resulting in a significant increase in side effects; , and the use of inaccurate clinical dosages affects the defects of drug efficacy

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Novel compound antihypertensive drug
  • Novel compound antihypertensive drug

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] A compound preparation containing the following components:

[0035] Nitrendipine 10mg

[0036] Metoprolol 12.5mg

[0037] Starch 55mg

[0038] Calcium Sulfate 20mg

[0039] Talc 2mg

[0040] Magnesium stearate 0.5mg

[0041] This embodiment can be made into compound nitrendipine-metoprolol tablet, and the preparation method can adopt the preparation method of common pharmaceutical preparations.

Embodiment 2

[0043] A compound preparation containing the following components:

[0044] Nitrendipine 10mg

[0045] Metoprolol 25mg

[0046] Starch 40mg

[0047] Calcium Sulfate 20mg

[0048] Talc 4mg

[0049] Magnesium Stearate 1mg

[0050] This embodiment can be made into compound nitrendipine-metoprolol tablet, and the preparation method can adopt the preparation method of common pharmaceutical preparations.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a compound preparation for curing hypertension. The compound antihypertensive drug comprises 5-20mg of nitrendipine and 5-50 mg of metoprolol. Aiming at solving the problem that currently when only one of nitrendipine and metoprolol is used clinically, in order to ensure the curative effect, the dosage of the drug is increased, which leads to obvious increase of the side effects, the invention provides a novel compound preparation. Nitrendipine and metoprolol are used together, so synergic and complementary curative effect can be produced. The novel compound antihypertensive drug enhances the tolerance of the patient, improves the compliance and reduces the dosage and the adverse reaction, and is convenient to take and cheap in price.

Description

technical field [0001] The invention relates to the technical field of medicine and discloses a new compound antihypertensive drug. Background technique [0002] Hypertension is the most common cardiovascular disease and a major public health problem worldwide. my country currently has about 100 million hypertensive patients. According to the epidemiological survey in 1991, the awareness rate of hypertension in my country's urban and rural areas was 36% and 13%, and the treatment rate was 17% and 5%, respectively. The form of hypertension prevention and treatment is quite severe. According to the forecast of WTO, by 2020, non-communicable diseases will account for 79% of the causes of death in my country, among which cardiovascular diseases will take the first place. [0003] Commonly used drugs for the treatment of hypertension include the calcium antagonist nitrendipine and the beta-blocker metoprolol. [0004] Nitrendipine (Nitrendipine), the chemical name is 2,6-dimet...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/435A61K31/138A61P9/12
Inventor 徐丽娟吴修艮陈进高瑞银聂丽云朱月华
Owner JIANGSU JIBEIER PHARMA
Features
  • Generate Ideas
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com