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Application of double-layer aseptic vacuum technique in external package of large volume injection

A vacuum technology and large-capacity technology, which is applied in the field of medical large-capacity injection manufacturing, can solve problems such as patient death, and achieve the effect of reducing medical accidents and ensuring physical health.

Inactive Publication Date: 2010-08-18
SICHUAN TAIPINGYANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Contaminated infusions were used on patients, which brought physical and mental pain to patients to varying degrees, and in severe cases resulted in death of patients

Method used

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  • Application of double-layer aseptic vacuum technique in external package of large volume injection
  • Application of double-layer aseptic vacuum technique in external package of large volume injection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0024] Take the non-PVC soft bag infusion bag as an example, and carry out the packaging of large-volume injections according to the following process:

[0025] Step 1: Cut the inner packaging bag in the aseptic workshop, and fill the liquid medicine in the inner packaging to form a large-volume injection.

[0026] Step 2: Pack the filled large-volume injections into protective outer packaging. This process is also carried out in the aseptic workshop.

[0027] The third step: the vacuum is drawn between the protective outer bag and the inner packaging to form a negative pressure, and the protective outer packaging is completely sealed. This process is also carried out in the aseptic workshop.

[0028] Step 4: Put the large-volume injection into the sterilization device for sterilization, the sterilization temperature is 121 degrees Celsius, and the duration: 20-30 minutes.

[0029] Step 5: Dry the sterilized large-volume injection, and then proceed to the subsequent process.

[0030] Ste...

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Abstract

The invention relates to application of a double-layer aseptic vacuum technique in the external package of large volume injection. The invention adopts a technical scheme comprising the following steps of: 1, filling medicinal liquid; 2, packaging the large volume injection into the external protective package and sealing; 3, vacuumizing a space between the internal package and the external package; 4, placing the package in a sterilizing device to sterilize; 5, drying; and 6, checking micro-leakage and removing the large volume injection which forms obvious water mist or droplet between the internal package and the external package. The external protective package can be PVC and non-PVC materials. Through the application, the large volume injection which forms micro-package in the internal package can be removed conveniently and effectively. At the same time, the application ensures that the internal package is under an aseptic condition and is not polluted from the sterilizing process to the use in medicinal places; and when used in the medicinal places with strict hygiene level requirement (such as a surgical operating room, an intensive care unit and the like), the internal package does not pollute the environments and does not carry bacteria into the medicinal places.

Description

Technical field [0001] The invention relates to the manufacturing field of a medical large-volume injection. Background technique [0002] Large-volume injections, which are used for intravenous infusion, include glass bottle infusion, plastic bottle infusion, soft bag infusion, and upright infusion bag, which can be packaged upright. [0003] Large-volume injections are directly used in human veins, and the safety of the liquid itself has an obvious impact on human life and health, so it is unnecessary to discuss it here. In order to ensure the safety of large-volume injections, in all production links, large-volume injections strive to achieve aseptic production. At present, the production process of large-volume injections is as large as: filling the liquid medicine to the inner packaging, sterilizing the filled large-volume injections, encapsulating the outer protective bag, and packing and leaving the factory. In medical places, use the protective outer bag immediately. [00...

Claims

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Application Information

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IPC IPC(8): B65B3/04B65B5/04B65B55/06B65D30/02A61J1/05A61J1/10
Inventor 张杰赵从康
Owner SICHUAN TAIPINGYANG PHARMA
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