Broad-spectrum contact type hemostatic medical fungicide and preparation method thereof
A bactericide and contact killing technology, applied to medical preparations containing active ingredients, antifungal agents, pharmaceutical formulas, etc., can solve the problems of ineffective penetration into the deep layer of the skin, limited bacteria species, and short duration , to achieve rapid bactericidal effect, long release time and wide application range
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Embodiment 1
[0022] Example 1: The broad-spectrum contact hemostatic medical bactericide is prepared from povidone iodine, chitosan, medical petrolatum, nonoxynol ether and purified water. The weight percentage of each component is polyvinyl alcohol. Vividone iodine 10%; chitosan 8%; medical petrolatum 5%; nonoxynol ether 2.5%; purified water 74.5%.
[0023] The preparation method is as follows:
[0024] The first step is to purchase the raw materials of each component according to the weight percentage of each component;
[0025] In the second step, put the petroleum jelly into the reactor and heat it up until the petroleum jelly is completely melted, then start the high-shear machine, and slowly add nonoxynol ether according to the proportioning requirements to emulsify the two into a microemulsion with blue light, and then cool to 50°C;
[0026] In the third step, the microemulsion with blue light obtained in the second step is pumped into another homogenization kettle, and then povidone iodin...
Embodiment 2
[0028] In Example 2, the weight content of each component is: povidone iodine 5%; chitosan 3%; medical petrolatum 3%; nonoxynol ether 1%; purified water 89%.
Embodiment 3
[0029] In Example 3, the weight content of each component is: povidone iodine 15%; chitosan 10%; medical petrolatum 10%; nonoxynol ether 5%; purified water 60%.
[0030] The preparation methods of Example 2 and Example 3 are the same as Example 1.
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