Broad-spectrum contact type hemostatic medical fungicide and preparation method thereof

A bactericide and contact killing technology, applied to medical preparations containing active ingredients, antifungal agents, pharmaceutical formulas, etc., can solve the problems of ineffective penetration into the deep layer of the skin, limited bacteria species, and short duration , to achieve rapid bactericidal effect, long release time and wide application range

Inactive Publication Date: 2010-09-01
JIANGSU PROVINCE JIANERKANG MEDICAL DRESSING CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disinfection effect of these conventional bactericidal disinfectants not only does not last for a long time, but also the bacteria that can be killed are limited. At the same time, this type of disinfection is highly irritating to the tissue, and it is used to scrub wounds, skin ulcers, and mucous membrane infections. Stimulating pain and injury to the patient, causing unbearable pain to the patient
At the same time, it cannot effectively penetrate deep into the skin, let alone stop bleeding

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1: The broad-spectrum contact hemostatic medical bactericide is prepared from povidone iodine, chitosan, medical petrolatum, nonoxynol ether and purified water. The weight percentage of each component is polyvinyl alcohol. Vividone iodine 10%; chitosan 8%; medical petrolatum 5%; nonoxynol ether 2.5%; purified water 74.5%.

[0023] The preparation method is as follows:

[0024] The first step is to purchase the raw materials of each component according to the weight percentage of each component;

[0025] In the second step, put the petroleum jelly into the reactor and heat it up until the petroleum jelly is completely melted, then start the high-shear machine, and slowly add nonoxynol ether according to the proportioning requirements to emulsify the two into a microemulsion with blue light, and then cool to 50°C;

[0026] In the third step, the microemulsion with blue light obtained in the second step is pumped into another homogenization kettle, and then povidone iodin...

Embodiment 2

[0028] In Example 2, the weight content of each component is: povidone iodine 5%; chitosan 3%; medical petrolatum 3%; nonoxynol ether 1%; purified water 89%.

Embodiment 3

[0029] In Example 3, the weight content of each component is: povidone iodine 15%; chitosan 10%; medical petrolatum 10%; nonoxynol ether 5%; purified water 60%.

[0030] The preparation methods of Example 2 and Example 3 are the same as Example 1.

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PUM

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Abstract

The invention discloses a broad-spectrum contact type hemostatic medical fungicide and a preparation method thereof. The fungicide comprises the following components in percentage by weight: 5 to 15 percent of povidone iodine, 3 to 10 percent of chitosan, 3 to 10 percent of petroleum jelly for medical purposes, 1 to 5 percent of nonoxinol, and the balance of purified water. After the fungicide is contacted with a wound surface or an affected part, the fungicide can depolymerize and release the contained iodine to achieve the function of sterilization. The product is the broad-spectrum powerful disinfectant, has strong killing effect on viruses, bacteria, fungi and mycoticspore, not only has long constant acting time, but also has small irritation to human skin, greatly reduces pains unbearable for ordinary people, and simultaneously has the function of hemostasis. The fungicide is applicable to skin and mucousmembrane infection, can be directly used for disinfecting graze, and is safe and convenient to use.

Description

【Technical Field】 [0001] The invention relates to a medical sterilizing and disinfecting agent, in particular to a sterilizing and disinfecting liquid used for sterilizing and disinfecting skin surfaces and wounds. 【Background technique】 [0002] At present, in the process of medical and clinical treatment, the disinfection and cleansing liquid for skin disinfection usually includes 3% hydrogen peroxide, 70% alcohol and iodine. The iodine is a liquid formed by dissolving iodine in an alcohol solution of potassium iodide. The specific method of use is to dip ordinary plastic cotton swabs in the bottled disinfection and cleaning solution, and then disinfect the skin, surgery and wounds, injection and puncture sites, oral cavity, vagina, utensils and other items. In the course of daily use, if it is used improperly, putting the used cotton swabs in the disinfection cleaning solution bottle again will cause cross infection. The disinfection effect of these conventional disinfectants...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/79A61K31/722A61P31/04A61P31/10A61P31/12A61P7/04
Inventor 陈国平缪震元张万年陈罗俊甘厚全孙建忠储小剑
Owner JIANGSU PROVINCE JIANERKANG MEDICAL DRESSING CO LTD
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