Compositions and methods for inhibiting the activation of dsRNA-dependent protein kinase and tumor growth inhibition
A technology of protein kinases and compositions, applied in the direction of antineoplastic drugs, drug combinations, active ingredients of heterocyclic compounds, etc.
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment
[0155] The disclosure is further defined in the following examples. It should be understood that, while indicating preferred embodiments, these Examples are given by way of illustration only. From the above discussion and these Examples, one skilled in the art can ascertain the preferred characteristics of this disclosure, and without departing from the spirit and scope thereof, can make various changes and modifications to adapt it to various usages and conditions.
[0156] Material
[0157] Fetal calf serum (FCS) and RPMI 1640 tissue culture medium were purchased from Invitrogen (Paisley, Scotland). L-[2,6- 3 H] phenylalanine (spec, act., 2.00TBqmmol -1 ), Hybond A nitrocellulose membrane and enhanced chemiluminescence (ECL) development kit were obtained from Amersham Biosciences (Bucks, UK). Antiphosphorabbit monoclonal antibodies and total PKR were purchased from New England Biolabs (Herts, UK). Rabbit polyclonal antiserum against phospho-eIF2α was obtained from Abcam...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com