Medicinal composition for treating depression and manufacturing method thereof

Abstract

The invention discloses a medicinal composition for treating depression, which is prepared by using liquoric root, white paeony root and extracts of the liquoric root and the white paeony root as raw materials. The invention also discloses a preparation method of the medicinal composition. Experiments show that: 1, after 2 days of stomach lavaging, the medicinal composition of the invention can reduce the dead time (P is less than 0.01) and forced swimming accumulated dead time (P is less than 0.05) of a suspended tail of a tested mouse obviously, so it is deduced that the medicinal composition of the invention has experimental depression resistant effect; 2, the combined use of the extracts of the liquoric root and the white paeony root in an optimal ratio achieves an anti-depression effect more advantageous over those obtained by the single use of the liquoric root and white paeony root; and 3, the 5-HT content and NE content of the brain of a chronic stress rat are reduced obviously. The medicinal composition of the invention can improve the 5-HT content and NE content of the brain of the chronic stress rat obviously, which may be one of the mechanisms through which the medicinal composition plays an anti-depression effect.

Description

technical field [0001] The invention relates to a group of medicinal compositions for treating depression made from licorice and white peony as raw materials, which can be used as medicine, nutritional agent and health food. [0002] The present invention also relates to a preparation method of the above-mentioned pharmaceutical composition for treating depression. Background technique [0003] Depression is a common illness. According to statistics, about 25% of women in the general population have experienced depression in their lifetime, and about 10% of men have experienced depression (Zhang Chunxing: "Modern Psychology"). Information provided by the World Health Organization: The incidence of depression in the world is about 11%. There are currently about 340 million mentally depressed patients in the world, and this number is still on the rise. The survey found that depression will increase in the next 20 years It is the second most common disease worldwide. [0004...

AI Technical Summary

Problems solved by technology

These drugs all have different degrees of side effects. Studies have shown that "the Fuan suppository contained in these drugs has an effect on balancing the body's functions, but more often than not, they still cannot calm the patient down.

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