Chinese medicinal detoxifying myo-regeneration paste for treating diabetic foot ulcer and preparation method thereof

A technology for detoxifying diabetic foot ulcers, detoxifying and promoting muscle growth, which can be used in medical formulas, medical preparations containing active ingredients, metabolic diseases, etc. The effect of related gene expression, protection of wound moisture, and no side effects

Inactive Publication Date: 2010-12-29
韩会民 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] (4) Surgical operations and interventional therapy: Arterial stents, balloon dilatation, arterial plaque ablation, arterial plaque atherectomy, artificial vascular bypass, etc. require sophisticated and expensive equipment, heavy trauma, high risk, high cost, and many complications , high mortality, poor patient compliance
[0007] (5) Stem cell therapy: The required equipment is sophisticated and expensive, and due to ethical restri

Method used

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  • Chinese medicinal detoxifying myo-regeneration paste for treating diabetic foot ulcer and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0041] Raw materials for preparing traditional Chinese medicine Jiedu Shengji Cream: 25g of rhubarb, 25g of coptis, 25g of cork, 60g of gypsum, 50g of comfrey, 60g of angelica, 30g of angelica, 10g of light powder, 30g of blood flower, and 100g of huangzhan.

[0042] Preparation steps:

[0043] a) 25g of rhubarb, 60g of gypsum, 50g of comfrey, 60g of angelica, and 30g of angelica are made into 0.5cm 3 The granules were immersed in 500ml of unsaturated fatty acid for one month, the unsaturated fatty acid mixture was poured into a temperature-controlled ointment apparatus, heated to 120°C with slow fire, and lasted for 45 to 60 minutes, and the residue was filtered to obtain filtrate A1.

[0044] b) Pour 30g of Xuelihua, 10g of light powder, and 100g of Huangzhan into a temperature-controlled ointment apparatus, heat slowly to fully mix the medicines, and remove residue to obtain filtrate B1.

[0045] c) Add filtrate B1 to filtrate A1, mix evenly, and seal for 7 days to obtain ...

Embodiment 2

[0049] Raw materials for preparing traditional Chinese medicine Jiedu Shengji Cream: 30g rhubarb, 37.5g coptis, 37.5g cork, 70g gypsum, 60g comfrey, 70g angelica, 35g angelica, 10g light powder, 35g blood flower, and 115g huangzhan.

[0050] According to the preparation steps of Example 1, the traditional Chinese medicine Jiedu Shengji Ointment D2 was prepared.

Embodiment 3

[0052] Raw materials for preparing traditional Chinese medicine Jiedu Shengji Cream: 35g rhubarb, 30g coptis, 30g cork, 70g gypsum, 60g comfrey, 70g angelica, 35g angelica, 25g light powder, 35g blood flower, and 115g huangzhan.

[0053] According to the preparation steps of Example 1, the traditional Chinese medicine Jiedu Shengji Ointment D3 was prepared.

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Abstract

The invention provides Chinese medicinal detoxifying myo-regeneration paste for treating diabetic foot ulcer, which belongs to the fields of traditional Chinese medical science and traditional Chinese medicines. The paste is prepared from the following raw materials in percentage by weight: 6 to 11 percent of rhubarb, 6 to 11 percent of golden thread, 6 to 11 percent of amur corktree bark, 14 to 19 percent of plaster, 12 to 17 percent of sinkiang arnebia root, 14 to 20 percent of Chinese angelica, 7 to 11 percent of angelica dahurica, 2 to 5 percent of calomel, 7 to 11 percent of dragon's blood and 23 to 30 percent of bee wax. Animal experiments and clinical researches prove that the Chinese medicinal detoxifying myo-regeneration paste provided by the invention has the effects of activating blood, dissolving stasis, removing putrefaction, regenerating myo, clearing away heat and toxic material and the like, has the advantages of keeping the surface of a wound wet, increasing the content of cell factors, namely, a vascular endothelial growth factor (VEGF) and a platelet-derived growth factor (PDGF) and promoting relevant gene expressions of muscles and blood vessels, along with definite curative effect, simple and convenient operation, economy, safety and no toxic or side effect and special significance in treating diabetic foot ulcer.

Description

Technical field: [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine detoxifying ointment for clinically treating diabetic foot ulcers and a production process thereof. Background technique: [0002] Diabetic foot ulcer is recognized as the first of the four obstinate complications in the world. It develops slowly, has a long course of disease, causes great pain, complex treatment, low curative effect, high cost, and high amputation rate. Every day, 2,880 people in the world amputate due to diabetic foot ulceration. The amputation rate of diabetic feet in foreign countries is as high as 50%, while the domestic amputation rate is 20%-30%. Diabetic patients have a significantly higher risk of lower limb gangrene than non-diabetic patients (about 15 times) ), the mortality rate of diabetic patients with foot ulcers is about twice that of diabetic patients without foot ulcers. The treatment cost of diabetic fo...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K9/06A61P3/10A61P17/02A61K33/06A61K33/28A61K35/64A61K35/644
Inventor 韩会民
Owner 韩会民
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