Effective part of chicory or jerusalem artichoke and preparation thereof

A technology of effective parts and chicory, applied in the field of effective parts of chicory and its preparations, can solve the problems of inconvenient carrying and taking, and achieve the effect of less impurity content, less loss and definite curative effect

Active Publication Date: 2011-02-02
BEIJING UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned medicines also provide some valuable basis for the treatment of hyperuricemia with traditional Chinese medicine, but most medicines have disadvantages such as inconvenient to carry and take.

Method used

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  • Effective part of chicory or jerusalem artichoke and preparation thereof
  • Effective part of chicory or jerusalem artichoke and preparation thereof
  • Effective part of chicory or jerusalem artichoke and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0165] Example 1: Chicory Granules

[0166] Preparation Process:

[0167] a. Pulverize: take the dried chicory pieces and pulverize them to the size of soybean grains (about 5 mm 3 );

[0168] b. Water extraction: The water extraction method is used to prepare the extract: the water extraction method is to place the crude drug of the size of soybean grain in water heated to 90 ° C, and extract 3 times for 1.5 hours each time. The volume of each water is the crude drug 10 times the amount;

[0169] c, purification: after the above-mentioned water extract is concentrated into a concentrated solution of 1: 1, the water extract of chicory is precipitated with 40% ethanol, filtered and recovered ethanol after 24-48 hours, and the effective part is obtained after drying under reduced pressure;

[0170] D, drying under reduced pressure: the above-mentioned thick extract is dried under reduced pressure to obtain medicinal powder;

[0171] e. Granulation and drying: add lactose equ...

Embodiment 2

[0173] Example 2: Chicory Tablets

[0174] Preparation Process:

[0175]a, pulverization: take the dried chicory decoction pieces, and pulverize it to the size of soybeans (about 5mm3);

[0176] b. Water extraction: the method of water extraction is used to prepare the extract: the water extraction method is to place the crude drug the size of soybean grains in water heated to 90°C, extract 3 times, each time for 1.5 hours, and the volume of each water is the crude drug 10 times the amount;

[0177] c. Purification: After the above-mentioned water extract is concentrated into a 1:1 concentrated solution, the chicory water extract is precipitated with 40% ethanol, filtered after 24-48 hours, and the ethanol is recovered, and the effective part is obtained after drying under reduced pressure;

[0178] d, drying under reduced pressure: the above-mentioned thick extract is dried under reduced pressure until dry to obtain a medicinal powder;

[0179] E, make tablet and dry: abov...

Embodiment 3

[0180] Embodiment 3: chicory capsules

[0181] Preparation Process:

[0182] a, pulverization: take the dried chicory decoction pieces, and pulverize it to the size of soybeans (about 5mm3);

[0183] b. Water extraction: the method of water extraction is used to prepare the extract: the water extraction method is to place the crude drug the size of soybean grains in water heated to 90°C, extract 3 times, each time for 1.5 hours, and the volume of each water is the crude drug 10 times the amount;

[0184] c. Purification: after concentrating the above water extract into a 1:1 concentrate, precipitate the chicory water extract with 40% ethanol, filter and recover ethanol after 24-48 hours to obtain 40% polysaccharide effective fraction;

[0185] d, drying under reduced pressure: the above-mentioned thick extract is dried under reduced pressure until dry to obtain a medicinal powder;

[0186] E, make tablet and dry: above-mentioned medicated powder adds the lactose that is equ...

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Abstract

The invention provides an effective part of chicory (or jerusalem artichoke) for preventing and curing hyperuricemia and a preparation thereof, wherein the effective part is prepared by the following method comprising the following steps of: extracting the chicory (or the jerusalem artichoke) with water for 1-5 times with 3-20 times of water at each time, wherein the extracting time at each time is 0.5-2.5 hours; and precipitating a chicory (or jerusalem artichoke) water extract with 40-percent ethanol, filtering and recovering the ethanol to obtain the 40-percent amylose effective part. The effective part has definite curative effect in the aspects of preventing and curing the hyperuricemia, can be used for preventing and curing the hyperuricemia, the hyperuricemia plus hypertriglyceridemia, the hyperuricemia plus hyperglycemia and the hyperuricemia plus blood hypercoagulation and blood hyperviscosity and has no obvious toxic or side effect or adverse reaction.

Description

technical field [0001] The invention relates to the effective part of chicory (or Jerusalem artichoke) and its preparation, belonging to the technical field of traditional Chinese medicine. Background technique [0002] Hyperuricemia is an important sign of gout and a group of diseases caused by purine metabolism disorders. With the acceleration of human life rhythm and the change of diet structure, the prevalence of hyperuricemia increases rapidly. In western developed countries, the prevalence of hyperuricemia is about 20%, and it increases with age. The current prevalence of hyperuricemia in my country is about 10%, and it has become the second largest metabolic disease in my country. Studies have fully shown that the incidence of hyperuricemia, the age of onset, and the geographical range of onset are all showing a trend of increasing and expanding. [0003] Hyperuricemia is not only an important sign of gout, but also closely related to various metabolic disorders. C...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08B37/00A61K36/28A61P19/06
Inventor 张冰刘小青林志健庄红艳
Owner BEIJING UNIV OF CHINESE MEDICINE
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