Process and apparatus for producing a tabletting aid and also a tabletting aid and tabletting mixture
An adjuvant and tableting technology, which is used in non-active ingredients in medical preparations, pill delivery, pharmaceutical formulations, etc. It can solve the problems of excessive mixing, low tablet hardness and tablet coverage, and save production time. and cost, low ejection force, high production speed
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[0044] Tableting aids according to the invention were compared in a placebo (Placebo), 40% acetaminophen (Paracetamol) and enalapril (Enalapril) with a list of physical mixtures consisting of the individual components. The results are given in Tables 2, 3 and 4.
[0045] ·Placebo tablets
[0046]
[0047] ★ Tableting aids according to the invention are only compressed at different pressures.
[0048] ★★ All components except PRUV were mixed for 15 minutes. Lubricant was then added, mixed for an additional 3 minutes and compacted at various pressures.
[0049] Table 2: Direct comparison between tableting aid (granulate 1) and physical mixture consisting of a single component;
[0051]
[0052] The DC-tabletting aids according to the invention show significantly better compressibility and tablet hardness, lower ejection forces and less abrasion than physical blends (Table 2, figure 1 and 2 ).
[0053] Acetaminophen (Paracetamol) tablets
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