Novel compound ethyl brevicate with pharmaceutical activity

Abstract

The invention relates to a novel compound of a structure formula (I). The compound can be extracted and separated from a dried whole plant of Erigeron breviscapus (Vant.) Hand. -Mazz. The compound has anti-inflammatory response, anti-platelet aggregation, anti-thrombotic and vasodilator effects, and can be used for preparing a medicament for treating cardiovascular and cerebrovascular diseases. The structure formula (I) is shown below.

Description

technical field The present invention relates to a novel compound with anti-inflammatory reaction, anti-platelet aggregation, anti-thrombosis and vasodilator effects, and a pharmaceutical composition for treating cardiovascular and cerebrovascular diseases containing the compound as an active ingredient. Specifically, it is a new compound Ethyl brevicate extracted from Erigeron breviscapus, its preparation method and its application in pharmacy. Background technique So far, the incidence of cardiovascular and cerebrovascular diseases represented by coronary heart disease and cerebral apoplexy (stroke) remains high, and its case fatality rate ranks first in the death rate of various human diseases. Finding new and effective drugs for the treatment of cardiovascular and cerebrovascular diseases is a difficult and hot spot that the pharmaceutical and clinical medicine circles are very concerned about. Erigeron breviscapus, also known as breviscapus, is the dried whole herb of...

AI Technical Summary

Problems solved by technology

Most of them are mixtures of multiple compounds. Although these drugs have therapeutic effects, the multiple components will inevitably cause the following problems: poor uniformity of curative effect, difficult quality control, and difficult to control side effects (injections are especially obvious)

The only effective drug for a single compound is breviscapine preparations, which is difficult to meet the complex clinical medical needs