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Pine pollen extract for treating fatty liver as well as preparation method and application thereof

A technology of pine pollen and fatty liver, which is applied in the field of plants, can solve the problems of poor patient compliance, long treatment period of fatty liver, slow onset of effect, etc., and achieve the effect of rapid absorption, strong treatment pertinence, and prevention of fatty liver

Active Publication Date: 2012-09-26
YANTAI NEW ERA HEALTH IND +1
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the treatment period for fatty liver is long, the onset of effect is slow, and the patient's compliance is poor, so the treatment is often ignored by people.

Method used

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  • Pine pollen extract for treating fatty liver as well as preparation method and application thereof
  • Pine pollen extract for treating fatty liver as well as preparation method and application thereof
  • Pine pollen extract for treating fatty liver as well as preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment Construction

[0027] 1. Preparation of aqueous extract of gymnosperm pine pollen for treating fatty liver:

[0028] 1. Sorting gymnosperm pine pollen: remove pollen impurities at room temperature.

[0029] 2. The removed gymnosperm pine pollen is air-flow crushed and wall-broken for 10 to 20 minutes.

[0030] 3. After soaking the pollen in water at normal pressure and temperature for 20-30 minutes, ultrasonically crush it for 20-40 minutes.

[0031]4. Remove solid impurities and take aqueous solution:

[0032] Centrifuge in a centrifuge with a rotational speed of 10000-16000 rpm for 10-15 minutes, and take the supernatant.

[0033] 5. The supernatant is ultrafiltered with a 3000D molecular sieve at an ambient temperature of 1-5°C to separate the gymnosperm pine pollen water extract with a molecular weight below 3000D, which is the water extract of pine pollen for treating fatty liver.

[0034] 2. Preparation of oral preparations and injection preparations:

[0035] 1. Preparation of ora...

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Abstract

The invention provides a pine pollen extract for treating fatty liver as well as a preparation method and an application thereof, relating to the technical field of extracting effective substances from gymnosperm pine pollen. The preparation method comprises the following steps: the pine pollen is subjected to wall breaking at a low temperature, and impurities in the pine pollen are removed; the pine pollen is extracted with ultrasonic after the pine pollen is immersed in normal-pressure normal-temperature water; solid impurities are centrifugally removed to obtain an aqueous solution; and a gymnosperm pine pollen aqueous extract with the molecular weight lower than 3,000D is separated at the environmental temperature of between 1 and 5 DEG C to obtain the gymnosperm pine pollen aqueous extract for treating the fatty liver. The pine pollen aqueous extract can be used for general health-care for children, and can prevent occurrence of fatty liver. The pine pollen aqueous extract can beused for preparing an oral preparation for treating the fatty liver, has a good absorption effect and low price, and also can be used for preparing an injection preparation for treating the fatty liver, which can be absorbed quickly, has strong treatment pertinence.

Description

technical field [0001] The invention relates to the technical field of extracting effective substances from plants, especially gymnosperm pine pollen. Background technique [0002] Fatty liver refers to the lesions caused by excessive accumulation of fat in liver cells due to various reasons. Fatty liver disease is seriously threatening the health of Chinese people and has become the second largest liver disease after viral hepatitis. It has been recognized as a hidden liver disease. Common causes of sclerosis. Fatty liver is a common clinical phenomenon rather than an independent disease. Its clinical manifestations are asymptomatic in mild cases, and violent in severe cases. Generally speaking, fatty liver is a reversible disease, early diagnosis and timely treatment can often return to normal. The formation of fatty liver is generally due to the imbalance between the decomposition and anabolism of fat in the liver, or the failure of transporting fat, and excessive accu...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/15A61P1/16
Inventor 周斌刘志河石丽花叶满红王桐于建伟鞠东尹利端李明乔强
Owner YANTAI NEW ERA HEALTH IND
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