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Traditional Chinese medicinal composition for treating breast cancer and preparation method thereof

A composition and breast cancer technology are applied in drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., which can solve the problems of no effect on breast cancer pain, unsatisfactory curative effect, toxicity, and side effects, etc., and achieve good results. Social value and economic benefits, high treatment costs, and large side effects

Inactive Publication Date: 2012-08-08
潘国芬
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Drug treatment generally adopts chemical drugs and Chinese patent medicines. Chemical drugs are effective quickly, but they cannot be cured, and they are more toxic and side effects, and the treatment cost is relatively high.
Although there are several medicines for treating this disease on the market at present, the curative effect is not satisfactory, and it has almost no effect on the pain of breast cancer. Pathological characteristics, combined with years of clinical experience, can well overcome the shortcomings of similar varieties currently on the market

Method used

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  • Traditional Chinese medicinal composition for treating breast cancer and preparation method thereof
  • Traditional Chinese medicinal composition for treating breast cancer and preparation method thereof
  • Traditional Chinese medicinal composition for treating breast cancer and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0059] The preparation method of honey refining pill for oral administration of the present invention: first extract 500g of scorpion and 500g of earthworm with ethanol to obtain the concentrated filtrate a of the extract, then 1000g of Radix Paeoniae Alba, 1000g of Codonopsis pilosula, 1000g of astragalus, 1000g of angelica, 1000g of drynariae, Subtilis 1000g, Gentiana 1000g, Comfrey 1000g, Atractylodes macrocephala 1000g, Garcinia 1000g, Poria cocos 1000g, Shijianchuan 1000g, psoralen 1000g, frankincense 1000g, Cyperus cyperi 1000g, Chonglou 1000g; crushed into coarse powder, further Pulverize, pass through 100 mesh to 120 mesh sieve, so that the amount of fine powder that can pass through the sieve reaches 30%, collect the fine powder that passes through the sieve to obtain fine powder b; then put the coarse powder that cannot pass through the 120 mesh sieve into a multi-functional extraction tank for extraction Twice, add 5-10 times the amount of water to decoct for 1-2 hou...

experiment example 2

[0077] Experimental example 2: long-term toxicity test data

[0078] 1. Experimental method

[0079] The guinea pigs were randomly divided into 4 groups, 15 in each group. Apply the depilatory agent evenly on both sides of the back spine of the guinea pig, so that the range of depilation is about 40 square centimeters. Clean the depilatory agent, observe each group of guinea pigs after 24 hours to be coated with respectively 0.2,0.4 and 0.8ml of the present invention's orally administered traditional Chinese medicine preparation Honey Refined Pills, contain crude drug 92,184 and 368mg respectively, another group is coated with vehicle 0.8ml twice a day, For 30 consecutive days, the general condition of the guinea pigs was observed. After the experiment, the animals were sacrificed for hematology, blood biochemical and pathological examinations.

[0080] 2. Results

[0081] No edema, hyperemia, erythema, bleeding spots and ulcers were found in the depilated trunk area of ​​g...

experiment example 3

[0082] Experimental example 3: Cumulative toxicity test:

[0083] Traditional Chinese medicine preparation of the present invention is taken orally honey refined pills to mice by 7.69, 19.18 and 43.21g crude drug / kg continuous medication 15 weeks (1.0ml / 100g body weight, every day 2 times) and after drug withdrawal 3 weeks, the result shows: Chinese medicine of the present invention The preparation has no obvious effect on the hair, behavior, defecation, body weight, organ weight, blood picture, liver and kidney function, blood sugar, blood lipid and other indicators of rats. After 1 week and 3 weeks after stopping the drug, there was no significant change in the organs of the rats. It shows that the oral capsule of the traditional Chinese medicine preparation of the present invention has little toxicity to rats after long-term administration, and there is no abnormal reaction after drug withdrawal, so the application is safe.

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Abstract

The invention discloses a traditional Chinese medicinal composition for treating breast cancer. In the traditional Chinese medicinal composition, the oral medicament is prepared from white peony root, pilose asiabell root, astragalus root, angelica, rhizoma drynariae, spica prunellae, radix gentianae, lithosperm root, rhizoma atractylodis macrocephalae, gamboges, scorpion, Tuckahoe, lumbricus, Chinese sage herb, fructus psoraleae, frankincense, nutgrass galingale rhizome and rhizoma paridis; and the external medicine is prepared from arisaema tuber, red sage root, prepared kusnezoff monkshoodroot, dahurian patrinia herb, suberect spatholobus stem, giant typhonium rhizome, frankincense, myrrh, szechuan lovage rhizome, mongolian dandelion herb, dahurian angelica, scorpion and ginger. The traditional Chinese medicinal composition has the advantages of strong targeting property with direct access to affected parts, low cost and the like, and is convenient for administration and manufacture. The traditional Chinese medicinal composition has the beneficial effects that traditional Chinese medicinal materials with different medicine properties are scientifically combined so as to reach ideal and safe therapeutic effect; by adopting oral and external administration modes, antitumor function can be realized, mammary tumor cells are eliminated and bone metastasis is inhibited, thus improving symptoms of a patient maximally, enhancing life quality and prolonging life; and the composition has low cost and is convenient to use, thus creating higher social value and higher economic benefit.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine composition for treating breast cancer and a preparation method thereof. Background technique [0002] Breast cancer is one of the most common malignant tumors in women. According to statistics, the incidence rate accounts for 7-10% of various malignant tumors in the whole body, and it is second only to uterine cancer in gynecological diseases. Its incidence is often related to heredity, and between the ages of 40 and 60, the incidence rate of women before and after menopause is higher. Only about 1-2% of breast cancer patients are men. Malignant tumors usually occurring in the glandular epithelium of the breast. It is one of the most common malignant tumors that seriously affects women's physical and mental health and even threatens their lives. Breast cancer is rare in men. Breast cancer is...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61K9/06A61P35/00A61K35/64A61K35/62A61K35/646
Inventor 潘国芬
Owner 潘国芬
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