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Interface layer wound dressing

一种伤口敷料、伤口的技术,应用在敷料、非粘性敷料、医药科学等方向,能够解决不能递送不同的药剂等问题,达到有成本效益、上皮形成增强、容易使用的效果

Active Publication Date: 2011-10-19
L R R D
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Neither prior art products are designed for rapid enzymatic debridement of the wound bed nor are prior art products capable of delivering different agents according to changing conditions in the interface layer and progressive stages of healing without removing the dressing layer without damaging the healing wound

Method used

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  • Interface layer wound dressing
  • Interface layer wound dressing
  • Interface layer wound dressing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0113] The wound dressing of the invention comprises a matrix of polymeric foam with polysaccharide coated conduits within the foam. Prior to deployment of the wound dressing on the wound surface, the conduit wall defines unoccupied or partially occupied compartments or channels within the stroma. During use, the polysaccharide becomes hydrated by absorbing wound exudate and thereby forms a gel which swells. Swelling polysaccharide almost completely and / or partially occupies previously unoccupied compartments or channels, but retains sufficient openness for gas and liquid between the two opposing outer surfaces of the foam, i.e. not in direct contact with the wound transmission between the outer surface of the bed and exposed to the external environment and the opposite outer surface in direct contact with the wound bed. The aforementioned opposing outer surfaces are also referred to herein as the "outward" and "inward" surfaces of the foam, respectively, with reference to th...

Embodiment 1

[0194] Common Example 1 .Management of a clean, viable dermal wound bed

[0195] The serous fluid secreted at the wound surface travels along the duct wall, is absorbed by the hyaluronic acid contained therein, and fully or partially hydrates the hyaluronic acid (as in figure 2 described in ), depending on the amount of fluid (moisture) at the wound surface. The wetting hyaluronic acid prevents drying of the healing wound, which enhances the epithelialization of the healing wound directed through the dressing surface. Complexation of hyaluronic acid with fibrin in the secreted fluid allows the dressing to adhere to the wound, forming an "artificial, reinforced scab" that prevents the proliferation of any foci of infection. when carried out as in image 3 When the epithelium is formed (usually over the dermal remnant) as described in , the keratinized epidermal layer separates the wound dressing from the wound. The detached wound dressing area can be cut away with scissors....

Embodiment 2

[0196] Common Example 2 .Management of wound beds with locally persistent eschar or light pollution

[0197] As described in General Example 1, the serous fluid secreted at the wound surface travels along the duct wall, is absorbed by hyaluronic acid, and hyaluronic acid is fully or partially hydrated (as in figure 2 described in ), depending on the amount of fluid (moisture) at the wound surface. The wetting hyaluronic acid prevents drying of the healing wound, which enhances the epithelialization of the healing wound directed through the dressing surface. The moist environment, along with the normal inflammatory response, promotes maceration ("autolysis") of eschar remnants and regression of contaminated foci. The autolysate absorbed by the hyaluronic acid along with the fibrin in the secreted fluid allows the dressing to adhere to the wound, forming an "artificial, reinforced scab" that prevents the proliferation of any foci of infection. As in common embodiment 1, car...

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PUM

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Abstract

The invention relates to a wound dressing and methods of preparation and use thereof for promoting healing of a wound bed. In particular, the wound dressing is advantageous for application to a debrided wound bed. The wound dressing comprises an open conduit polymeric foam matrix, and a hydrophilic polymer which is disposed in dry form on the inner surfaces of the conduits within the matrix.

Description

field of invention [0001] The present invention relates to wound dressings and their use, in particular for the treatment of debrided wound beds. The dressing comprises an open catheter polymer foam matrix and a hydrophilic polysaccharide disposed in dry form on the inner surface of the catheter within the matrix. Background of the invention [0002] Skin wounds disrupt the continuity of the protective tissue interface between the body's internal organs and the external environment. Causes of skin wounds include burns caused by exposure to thermal extremes, radiation (UV or ionizing) or chemicals; mechanical injury and pathological conditions with necrotic complications particularly associated with diabetes, hypertension and vascular diseases. [0003] Wound bed preparation (WBP) refers to medical intervention activities aimed at any or all of the following: cleansing the wound bed of any foreign material and / or dead tissue (e.g. eschar in the case of burned skin); increasi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F13/00A61F15/00
CPCA61F13/00063A61F13/00991A61F2013/00157A61F2013/00165A61F2013/00255A61F2013/00285A61F2013/00323A61F2013/00519A61F2013/0054A61F2013/00634A61F2013/0074A61F2013/00748A61F2013/0091A61F2013/00927A61F2013/00931A61L15/28A61L15/425A61L15/60A61F13/01008A61L15/30
Inventor 利奥尔·罗森伯格
Owner L R R D