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Asthma-relieving composite and preparation method and application thereof

A composition and an anti-asthma technology, applied in the field of anti-asthmatic compositions and their preparation, can solve the problems of complex Chinese patent medicines, inconvenient to carry, poor stability and the like

Inactive Publication Date: 2011-11-16
河北凯威制药有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the complex composition of Chinese patent medicines, solution preparations often have problems such as poor stability and inconvenient portability.

Method used

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  • Asthma-relieving composite and preparation method and application thereof
  • Asthma-relieving composite and preparation method and application thereof
  • Asthma-relieving composite and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0116] A traditional Chinese medicine compound anti-asthma dripping pill for oral administration, which is a medicament prepared from Ephedra, Ficus lobata, Dajinhua, and polyethylene glycol 6000 in the following proportions by weight:

[0117] Ephedra 450

[0118] Small leaf banyan 300

[0119] Yang Jinhua 150

[0120] Polyethylene glycol 6000 400

[0121] The preparation technology of Chinese medicine compound antiasthma dripping pill of the present invention is described in detail below:

[0122] (1) Preparation of extracts: Fangzhong Sanwei, Ephedra, Ficus microphylla and Yangjinhua, extract 2 times with 15 times the amount of acid aqueous solution (0.05%), 1.5 hours each time, filter, combine the filtrates, and depressurize at 65°C Concentrate into a thick paste (medicine: thick paste = 2:1). Add ethanol under rapid stirring to make the alcohol content 70%, let it stand overnight, take the supernatant and filter, recover ethanol from the filtrate, concentrate under re...

Embodiment 2

[0126] A traditional Chinese medicine compound anti-asthma dripping pill for oral administration, which is a medicament prepared from ephedra, ficus lobata, licorice, daphnia japonica, and polyethylene glycol 4000 in the following proportions by weight:

[0127] Ephedra 400

[0128] Small leaf banyan 200

[0129] Licorice 50

[0130] Datura 100

[0131] Polyethylene glycol 4000 350

[0132] The preparation technology of Chinese medicine compound antiasthma dripping pill of the present invention is described in detail below:

[0133] (1) Preparation of extracts: Fangzhong four flavors, ephedra, fig, licorice and datura, extracted twice with 18 times the amount of acid aqueous solution (0.01%), 1 hour each time, filtered, combined filtrate, 60 Concentrate under reduced pressure at ℃ to form a thick ointment (medicinal material: thick ointment = 2:1). Add ethanol under rapid stirring to make the alcohol content 60%, let stand overnight, take the supernatant and filter, recov...

Embodiment 3

[0137] A traditional Chinese medicine compound anti-asthma dripping pill for oral administration, which is a medicament prepared from ephedra, licorice, datura macrogol 6000, and macrogol 4000 in the following proportions by weight:

[0138] Ephedra 500

[0139] Licorice 100

[0140] Datura 200

[0141] Polyethylene glycol 6000 200

[0142] Polyethylene glycol 4000 300

[0143] The preparation technology of Chinese medicine compound antiasthma dripping pill of the present invention is described in detail below:

[0144] (1) Preparation of extracts: Sanwei, ephedra, licorice and Yangjinhua, extracted twice with 16 times the amount of acid aqueous solution (0.02%), 1.5 hours each time, filtered, combined filtrates, and concentrated under reduced pressure at 70°C into thick ointment (herb: thick ointment = 2:1). Add ethanol under rapid stirring to make the alcohol content 65%, let it stand overnight, take the supernatant and filter, recover the ethanol from the filtrate, con...

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Abstract

The invention discloses an asthma-relieving composite and a preparation method and application thereof. The asthma-relieving dripping pill comprises ephedra, X, datura flowers and an auxiliary agent , wherein X is ficus microcarpa and / or liquorice; and the auxiliary agent is polyethylene glycol 6000 or 4000. The asthma-relieving composite disclosed by the invention plays roles of relieving asthma, relaxing tracheal smooth muscles and relieving cough, can be used for preparing the drugs for treating asthma and cough diseases and has popularization and application values.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compositions, in particular to an anti-asthma composition and its preparation method and application. Background technique [0002] Asthma is one of the most common diseases in clinical practice. No matter in the past or now, it is considered as one of the more difficult diseases by traditional Chinese medicine or Western medicine. At present, there is still a lack of ideal Chinese and Western medicines. [0003] According to the world's first asthma day (98.12.11), there are 150 million people in the world, and 25 million people in China suffer from asthma. According to reports, the current incidence of asthma in the world is 1-3%, and the morbidity and mortality in most countries are still increasing year by year. About 1 million people die of asthma in my country every year, and 5-10 million people are disabled. And the difficulty of radical cure has become a problem of social co...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/81A61P11/06A61P11/14
Inventor 朱盛山李苑新
Owner 河北凯威制药有限责任公司
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