A traditional Chinese medicine composition for improving hypoxia tolerance and its preparation method and application
A composition and tolerance technology, applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, can solve the problems of inconvenience to take, large toxic and side effects, and achieve enhanced anti-stress ability and strict compatibility. , the effect of reasonable prescription design
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Embodiment 1
[0025] Embodiment 1: the preparation of granule
[0026] Take 30g Rhodiola rosea, 40g Shichangpu, 20g wolfberry fruit and 20g dogwood medicinal materials and mix them, add water to decoct twice, add water for the first time to 8 times the weight of the medicinal materials, decoct for 1 hour, and add water for the second time to equal the weight of the medicinal materials 6 times the amount, decoct for 1 hour, combine the decoction, filter, concentrate the filtrate to a relative density of 1.10 (65°C), add an appropriate amount of ethanol to make the alcohol content (volume fraction) reach 65%, stir, stand for 24 hours, and filter , the filtrate recovers ethanol and concentrates it to an extract with a relative density of 1.20 (65°C), which is spray-dried (conditions are that the inlet air temperature is 100°C, the outlet air temperature is 80°C, the material temperature is 70°C, and the atomization pressure is 0.2 M Pa, the spray speed is 5ml / s.), crushed into dry extract powd...
Embodiment 2
[0027] Embodiment 2: the preparation of tablet
[0028] Take 40g of rhodiola rosea, 30g of calamus calamus, 25g of wolfberry fruit and 15g of dogwood medicinal materials and mix them, add water to decoct twice, add water for the first time to 10 times the weight of the medicinal materials, decoct for 1.5h, add water for the second time to obtain the weight of the medicinal materials 8 times the amount of the decoction, decocted for 1.5h, combined the decoction, filtered, the filtrate was concentrated to a relative density of 1.15 (65°C), added an appropriate amount of ethanol to make the alcohol content (volume fraction) reach 75%, stirred, and stood for 24 hours. Filtrate, recover ethanol from the filtrate and concentrate to extract with a relative density of 1.25 (65°C), spray-dry (conditions are that the inlet air temperature is 120°C, the outlet air temperature is 90°C, the material temperature is 80°C, and the atomization pressure is 0.3 MPa, the spray speed is 7.5 / s.), c...
Embodiment 3
[0029] Embodiment 3: the preparation of oral liquid
[0030] Take 40g of rhodiola rosea, 30g of calamus calamus, 25g of medlar and 15g of dogwood medicinal materials and mix them, add water to decoct twice, add water for the first time to 12 times the weight of the medicinal materials, decoct for 2 hours, and add water for the second time to equal the weight of the medicinal materials 10 times the amount, decoct for 2 hours, combine the decoction, filter, concentrate the filtrate to a relative density of 1.20 (65°C), add an appropriate amount of ethanol to make the alcohol content (volume fraction) reach 85%, stir, stand for 24 hours, and filter , the filtrate recovers ethanol and concentrates to an extract with a relative density of 1.30 (65°C), which is spray-dried (conditions are that the inlet air temperature is 100°C, the outlet air temperature is 90°C, the material temperature is 90°C, and the atomization pressure is 0.4 M Pa, spray speed is 10 / s.), crushed into dry extr...
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