A kind of spirulina active polysaccharide and preparation method thereof

Abstract

The invention relates to an active spirulina polysaccharide and a preparation method thereof. By introducing an activity evaluation index, discussing the influence of a raw material pretreatment method and different extraction processing technologies on spirulina polysaccharide yield, polysaccharide preservation rate, protein removal rate and polysaccharide lipid peroxidation resistance and evaluating and screening an extraction processing technology capable of well keeping the bioactivity of the spirulina polysaccharide and with relatively high spirulina polysaccharide yield, the active spirulina polysaccharide is prepared by preferable process conditions; the main active ingredients of the active spirulina polysaccharide are binding protein polysaccharides, the molecular weights of which are 100,000 and 95,000 respectively; the active spirulina polysaccharide has remarkable hepatic tissue lipid peroxidation activity resistance; and the two binding protein polysaccharides are qualitycontrol index ingredients of a spirulina lipid peroxidation activity resistant polysaccharide product. Compared with a method discussed in the conventional technology, the protection of the extraction, separation and purification processes on the activity of the spirulina polysaccharide is stressed; and by comprehensively evaluating and optimizing the preparation process conditions, blindness of the process discuss and destroy and loss of the active ingredients in the extraction and purification processes can be greatly reduced.

Description

Technical field [0001] The invention belongs to the field of natural product preparation, and more specifically relates to a spirulina active polysaccharide and a preparation method thereof. Background technique [0002] Polysaccharides are important biological macromolecules in organisms, supporting tissues and important energy sources in animals and plants. In recent years, a large number of studies on polysaccharides and sugar complexes have shown that polysaccharides have special biological activities and can improve the immune function of the body. Sugar participates in all important life activities. People's early research on polysaccharides mostly focused on the biological activity of medicinal plant polysaccharides, such as the activity of Astragalus and Ganoderma lucidum polysaccharides. With the rise of marine drugs, the research on the activity of seaweed polysaccharides has become the focus of current drug research. There have been a large number of literature repor...

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Problems solved by technology

There have been a large number of literature reports on the pharmacological research and preparation technology research of spirulina polysaccharides, but the relevant research on the relationship between pharmacological activity and extraction and separation methods has not been reported. Incomplete pharmacological and technological research has led to The biological activity of spirulina polysaccharide is greatly reduced

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