The invention discloses a residual oil distribution rule quantitative analysis method, which comprises the following steps of: step 1, establishing a grid system, and simulating a well and an artificial crack by using a local grid encryption technology; step 2, inputting basic parameters such as porosity, permeability, original saturation and the like, determining the size of a water body, and selecting a relative permeability curve; step 3, carrying out sensitivity quantitative analysis on the parameters, and carrying out optimal design on a digital-analog scheme by using a method related toan orthogonal test; and step 4, taking oil field production dynamic data as a basis of historical fitting, and carrying out comprehensive inspection on the established model. According to the residualoil distribution law quantitative analysis method, orthogonal test design is introduced, the factor combination and quantity of a digital-analog scheme are determined, the distribution law of underground oil, gas and water is reflected more accurately through historical fitting, a large amount of manpower, material resources and time are saved, and the method has the characteristic of high applicability and is suitable for popularization and application.