Application of Cathelicidin-bf Antimicrobial Peptide from Golden Krait
A technology of antibacterial peptide and action of golden ring snake, which can be applied in the field of biomedicine and can solve the problem that the active ingredients of drugs cannot function better.
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[0026] The following examples are used to further illustrate the essential content of the present invention, but the content of the present invention is not limited thereto.
[0027] 1. To investigate the sensitivity of two common bacterial vaginosis pathogens (Staphylococcus aureus and Escherichia coli) to cathelicidin-BF
[0028] 1. Material
[0029] 1.1 Strains: Staphylococcus aureus (11 strains) and Escherichia coli (10 strains) isolated from patients with bacterial vaginosis infection.
[0030] 1.2 Medium nutrient agar, broth, Mueller-Hinton (MH) agar medium (bacteria), sand castle agar medium.
[0031] 1.3 Drugs: chemical synthesis of cathelicidin-BF, bacitracin, ciprofloxacin, ampicillin and azithromycin.
[0032] 2 Investigate the sensitivity of drug-resistant bacteria to cathelicidin-BF
[0033] 2.1 The agar plate dilution method was used to determine the MIC of cathelicidin-BF to Staphylococcus aureus and E. coli. Take 12 sterile test tubes (10ml) and arrange them in a row. Ad...
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