High-transparency and high-toughness degradable material for outer tube of disposable syringe

Abstract

The invention discloses a high-transparency and high-toughness degradable material for the outer tube of a disposable syringe, which is characterized in that the high-transparency and high-toughness degradable material consists of the following raw materials by weight portions: 100 portions of polylactic acid, 5-20 portions of plasticizer, 5-15 portions of toughening agent, 0.1-0.3 portion of nucleating agent, 0.2-0.5 portion of antioxidant and 0.1-1 portion of lubricant. The high-transparency and high-toughness degradable material for the outer tube of the disposable syringe has the advantages that the formula is reasonable, the transparency and the toughness are high, the material is degradable, the degradation speed is fast, the syringe can be destroyed automatically and the decomposition products do no harm to the environment.

Description

technical field

[0001] The invention relates to the field of medical materials, in particular to a high-transparency and high-toughness degradable material for a disposable syringe jacket. Background technique

[0002] The commonly used materials for disposable syringes used today are petroleum-based plastics (such as polypropylene). Although the problem of cross-infection has been solved, the used ones are basically disposed of by incineration, which brings serious pollution to the environment. Polylactic acid is a biodegradable and environmentally friendly aliphatic polyester. The renewability of its synthetic raw materials and low pollution in the production process provide an excellent basis for the development and application of polylactic acid. It is very advantageous in the application of molecular materials. At present, many manufacturers are making great efforts in degradation. Domestic manufacturers have introduced disposable syringes made of polylactic acid degra...

Examples

Embodiment 1

[0045] Weigh 100kg of polylactic acid, and dry it for 24 hours at a temperature of 40°C and a vacuum of 0.05MPa; then mix it with 5kg tributyl citrate, 5kg POE, 0.1kg bis(3,4-dimethylphenyl Methyl)sorbitol, 0.1kg (2,4-di-tert-butylphenyl)phosphite triester, 0.05kg tetrakis[β-(3,5-di-tert-butyl-4-hydroxyphenyl)propionic acid] Add pentaerythritol ester and 0.1kg ethylene bisstearamide together into the high-mixer and stir for 3-5 minutes to obtain high-mixture for later use; finally, put the obtained high-mixture into a twin-screw extruder to extrude and granulate, and the granulation temperature : 170-220°C, screw speed: 350-400r / min, and then water-cooled to obtain a high-transparency, high-toughness degradable material for a disposable syringe jacket.

Embodiment 2

[0047] Weigh 100kg of polylactic acid and dry it for 24 hours at a temperature of 45°C and a vacuum of 0.05MPa; then mix it with 12kg of tributyl citrate, 10kg of POE, 0.2kg of bis(3,4-dimethylbenzene Methyl)sorbitol, 0.2kg (2,4-di-tert-butylphenyl)phosphite triester, 0.1kg tetrakis[β-(3,5-di-tert-butyl-4-hydroxyphenyl)propionic acid] Add pentaerythritol ester and 0.5kg ethylene bisstearamide together into the high-mixer and stir for 3-5 minutes to obtain a high-mixture for later use; finally put the obtained high-mixture into a twin-screw extruder to extrude and granulate, and the granulation temperature : 170-220°C, screw speed: 350-400r / min, and then water-cooled to obtain a high-transparency, high-toughness degradable material for a disposable syringe jacket.

Embodiment 3

[0049] Weigh 100kg of polylactic acid, and dry it for 24 hours at a temperature of 50°C and a vacuum of 0.05MPa; then mix it with 20kg tributyl citrate, 15kg POE, 0.3kg bis(3,4-dimethylphenyl Methyl)sorbitol, 0.3kg (2,4-di-tert-butylphenyl)phosphite triester, 0.15kg tetrakis[β-(3,5-di-tert-butyl-4-hydroxyphenyl)propionic acid] Add pentaerythritol ester and 1kg ethylene bisstearamide together into the high-mixer and stir for 3-5 minutes to obtain a high-mixture; finally put the obtained high-mixture into a twin-screw extruder to extrude and granulate. The granulation temperature is: 170-220°C, screw speed: 350-400r / min, and then water-cooled to obtain a high-transparency, high-toughness degradable material for a disposable syringe jacket.

technical field

[0001] The invention relates to the field of medical materials, in particular to a high-transparency and high-toughness degradable material for a disposable syringe jacket. Background technique

[0002] The commonly used materials for disposable syringes used today are petroleum-based plastics (such as polypropylene). Although the problem of cross-infection has been solved, the used ones are basically disposed of by incineration, which brings serious pollution to the environment. Polylactic acid is a biodegradable and environmentally friendly aliphatic polyester. The renewability of its synthetic raw materials and low pollution in the production process provide an excellent basis for the development and application of polylactic acid. It is very advantageous in the application of molecular materials. At present, many manufacturers are making great efforts in degradation. Domestic manufacturers have introduced disposable syringes made of polylactic acid degra...

Examples

Embodiment 1

[0045] Weigh 100kg of polylactic acid, and dry it for 24 hours at a temperature of 40°C and a vacuum of 0.05MPa; then mix it with 5kg tributyl citrate, 5kg POE, 0.1kg bis(3,4-dimethylphenyl Methyl)sorbitol, 0.1kg (2,4-di-tert-butylphenyl)phosphite triester, 0.05kg tetrakis[β-(3,5-di-tert-butyl-4-hydroxyphenyl)propionic acid] Add pentaerythritol ester and 0.1kg ethylene bisstearamide together into the high-mixer and stir for 3-5 minutes to obtain high-mixture for later use; finally, put the obtained high-mixture into a twin-screw extruder to extrude and granulate, and the granulation temperature : 170-220°C, screw speed: 350-400r / min, and then water-cooled to obtain a high-transparency, high-toughness degradable material for a disposable syringe jacket.

Embodiment 2

[0047] Weigh 100kg of polylactic acid and dry it for 24 hours at a temperature of 45°C and a vacuum of 0.05MPa; then mix it with 12kg of tributyl citrate, 10kg of POE, 0.2kg of bis(3,4-dimethylbenzene Methyl)sorbitol, 0.2kg (2,4-di-tert-butylphenyl)phosphite triester, 0.1kg tetrakis[β-(3,5-di-tert-butyl-4-hydroxyphenyl)propionic acid] Add pentaerythritol ester and 0.5kg ethylene bisstearamide together into the high-mixer and stir for 3-5 minutes to obtain a high-mixture for later use; finally put the obtained high-mixture into a twin-screw extruder to extrude and granulate, and the granulation temperature : 170-220°C, screw speed: 350-400r / min, and then water-cooled to obtain a high-transparency, high-toughness degradable material for a disposable syringe jacket.

Embodiment 3

[0049] Weigh 100kg of polylactic acid, and dry it for 24 hours at a temperature of 50°C and a vacuum of 0.05MPa; then mix it with 20kg tributyl citrate, 15kg POE, 0.3kg bis(3,4-dimethylphenyl Methyl)sorbitol, 0.3kg (2,4-di-tert-butylphenyl)phosphite triester, 0.15kg tetrakis[β-(3,5-di-tert-butyl-4-hydroxyphenyl)propionic acid] Add pentaerythritol ester and 1kg ethylene bisstearamide together into the high-mixer and stir for 3-5 minutes to obtain a high-mixture; finally put the obtained high-mixture into a twin-screw extruder to extrude and granulate. The granulation temperature is: 170-220°C, screw speed: 350-400r / min, and then water-cooled to obtain a high-transparency, high-toughness degradable material for a disposable syringe jacket.