Proteoglycan protein tablet and preparation method thereof

A technology of polysaccharide protein and protein, which is applied in the direction of pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc., to achieve the effect of enhancing infiltration

Active Publication Date: 2014-05-28
嘉善瑞佳运动器材有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(Wang Yufen, Han Shuanghong, Qu Shuming etc., the research of anti-aging effect of centipede, Chinese Journal of Traditional Chinese Medicine, 1994,19 (11): 685) but, through retrieval, do not have a kind of adopt mushroom class polysaccharide protein and centipede polysaccharide protein so far Oral preparations such as tablets or capsules are disclosed or used

Method used

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  • Proteoglycan protein tablet and preparation method thereof
  • Proteoglycan protein tablet and preparation method thereof
  • Proteoglycan protein tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0101] (1) Pour 2 kg of white mushroom extract into an evaporating dish, heat at 80°C and keep stirring for 2 hours to make a thick paste;

[0102] (2) Add 3.0 kg of calcium sulfate and 0.3 kg of gelatin, continue heating at 80°C and stir for 2 hours to make the mixture into a thick paste;

[0103] (3) spread the thick paste in step (2) on a stainless steel plate, put it in an oven and dry at 80°C for 24 hours to obtain a dry paste;

[0104] (4) the dry paste in step (3) is pulverized into fine powder;

[0105] (5) Take by weighing 0.6 kg of the above-mentioned centipede polysaccharide-protein complex and grind into fine powder;

[0106] (6) take by weighing 0.7 kilogram of lentinan protein, 0.5 kilogram of ganoderma lucidum polysaccharide protein and grind into fine powder;

[0107] (7) Mix the fine powder of steps (4), (5) and (6) evenly, then add 2.5 kg of calcium sulfate and mix evenly to make granules, after drying at 80°C, add 0.4 kg of magnesium stearate The lubrican...

Embodiment 2

[0110] (1) Pour 2.5 kg of white mushroom extract into an evaporating dish, heat at 90°C and keep stirring for 2 hours to make a thick paste;

[0111] (2) Add 3 kg of calcium sulfate and 0.8 kg of gelatin, continue heating at 80°C and stir for 1 hour to make the mixture into a thick paste;

[0112] (3) Spread the thick paste in step (2) on a stainless steel plate, put it in an oven and dry it at 70°C for 24 hours to obtain a dry paste;

[0113] (4) the dry paste in step (3) is pulverized into fine powder;

[0114] (5) Take by weighing 0.7 kg of the above-mentioned centipede polysaccharide-protein complex and grind into fine powder;

[0115] (6) take by weighing 0.8 kilogram of lentinan protein, 0.6 kilogram of ganoderma lucidum polysaccharide protein and grind into fine powder;

[0116] (7) Mix the fine powder of steps (4), (5) and (6) evenly, add 1.1 kg of calcium sulfate and mix evenly to make granules, after drying at 70°C, add 0.5 kg of magnesium stearate for lubrication ...

Embodiment 3

[0119] (1) Pour 2.2 kg of white mushroom extract into an evaporating dish, heat at 70°C and keep stirring for 2 hours to make a thick paste;

[0120] (2) Add 2.5 kg of calcium sulfate and 0.9 kg of gelatin, continue heating at 60°C and stir for 1 hour to make the mixture into a thick paste;

[0121] (3) Spread the thick paste in step (2) on a stainless steel plate, put it in an oven and dry it at 70°C for 24 hours to obtain a dry paste;

[0122] (4) the dry paste in step (3) is pulverized into fine powder;

[0123] (5) Take by weighing 0.9 kg of the above-mentioned centipede polysaccharide-protein complex and grind it into fine powder;

[0124] (6) take by weighing 0.5 kilogram of lentinan protein, 0.8 kilogram of ganoderma lucidum polysaccharide protein and grind into fine powder;

[0125] (7) Mix the fine powder of steps (4), (5) and (6) evenly, add 1.9 kg of calcium sulfate and mix evenly to make granules, after drying at 70°C, add 0.3 kg of magnesium stearate for lubrica...

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Abstract

The invention discloses a proteoglycan protein tablet and a preparation method thereof. The proteoglycan protein tablet is prepared from the following raw materials in percentage by weight: 10-15 percent of white mushroom extract, 5-10 percent of lucid ganoderma proteoglycan proteins, 5-10 percent of mushroom proteoglycan proteins, 5-10 percent of centipede proteoglycan protein compound, 50-60 percent of calcium sulfate, 3-10 percent of gelatin and 2-6 percent of magnesium stearate, wherein in the terms of glucose, every milliliter of white mushroom extract used in the tablet comprises 3-15 mg of proteoglycans and 8-40 mg of total amino acid, wherein the 8-40 mg of total amino acid comprises 3-20 mg of glutamic acid and 0.8-5 mg of aspartic acid. The preparation method comprises the following steps of: uniformly mixing fine powder; adding an appropriate amount of calcium sulfate for uniformly mixing to obtain particles; drying; adding an appropriate quantity of lubricating agent; and tableting with a tableting machine. The proteoglycan protein tablet can be taken as a medicament for treating or preventing tumors, a medicament for treating or preventing leukopenia, a medicament for treating or preventing light and medium icteric hepatitis, and a medicament for treating or preventing neurasthenia.

Description

Technical field: [0001] The present invention relates to a polysaccharide protein tablet and a preparation method thereof, in particular to a tablet that can significantly increase white blood cells, improve liver function, regulate nervous system functions, improve human immunity, and be used for leukopenia, infectious hepatitis, neurasthenia and other diseases. Polysaccharide protein tablets for adjuvant therapy. Background technique: [0002] Since the antitumor activity of fungal polysaccharides was discovered, fungal polysaccharides have attracted more and more attention and become a very active research field. It has been found that fungal polysaccharides have complex biological activities and functions, among which the most important activity is immunomodulatory activity. As an immunomodulator, fungal polysaccharides have been widely used in diseases such as immunity, deficiency diseases, autoimmune diseases and tumors. clinical treatment. [0003] Mushroom polysacc...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/074A61K9/20A61P1/16A61P7/00A61P25/20A61P31/14A61P37/04A61K35/64A61K35/648
Inventor 柯依坤
Owner 嘉善瑞佳运动器材有限公司
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