Compounds for the treatment of metabolic disorders
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- PROSIDION LIMITED
- Publication Date
- 2012-03-28
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
technical field
[0001] The present invention relates to therapeutic compounds useful in the treatment of metabolic diseases including type II diabetes. In particular, the invention relates to compounds having activity as GPR119 agonists. Background technique
[0002] Drugs targeting the pathophysiology associated with non-insulin-dependent type II diabetes have many potential side effects and are underutilized for dyslipidemia and hyperglycemia in a high proportion of patients. Treatment typically uses diet, exercise, hypoglycemic agents, and insulin to focus on the needs of the individual patient, but there is a continuing need for new antidiabetic drugs, especially those that are better tolerated and have fewer adverse effects.
[0003] Likewise, metabolic syndrome (syndrome X) puts humans at high risk for coronary artery disease and is characterized by a set of risk factors including central obesity (excess fat tissue in the abdomen), Glucose intolerance, high triglycer...