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Radiation-proof traditional Chinese medicinal composition and preparation method and application thereof

A composition and radiation protection technology, applied in the directions of drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of difficult radiation protection, aggravated radiation damage, etc., and achieve the improvement of leukopenia, prevention and treatment of radiation damage. , Improve the effect of peripheral blood leukopenia

Inactive Publication Date: 2013-09-04
JINAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

In addition to patients, doctors and nurses who perform medical diagnosis and radiotherapy are often directly exposed to radiation, making radiation protection more difficult and radiation damage aggravated

Method used

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  • Radiation-proof traditional Chinese medicinal composition and preparation method and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Preparation of radiation-proof traditional Chinese medicine composition: Weigh 5 grams of white plum, 5 grams of weeping grass, 5 grams of geranium, 5 grams of ramie root and 5 grams of saponins, and add 9 times the total weight of the above-mentioned traditional Chinese medicine raw materials after mixing. Soak in water for 2 hours, heat and decoct for 2 hours, filter; add 8 times the total weight of each traditional Chinese medicine raw material to the dregs, heat and decoct for 1 hour, filter, and combine the filtrates to obtain the water decoction of the radiation-proof traditional Chinese medicine composition.

Embodiment 2

[0026] The preparation of the radiation-proof traditional Chinese medicine composition:

[0027] (1) Weigh 120 grams of white plum, 180 grams of weeping grass, 180 grams of geranium, 120 grams of ramie root and 120 grams of saponin thorn, add the water of 8 times the total weight of the above-mentioned traditional Chinese medicine raw materials after mixing, soak for 2 hours, and heat Decoct for 2 hours, filter; add water with 8 times the total weight of each traditional Chinese medicine raw material to the dregs, heat for 1.5 hours, filter, combine the filtrates, and stand to separate the solids to obtain the supernatant;

[0028] (2) Concentrate the supernatant to a relative density of 1.05, and send it into a spray dryer for spray drying. The inlet air temperature is 140° C., the outlet air temperature is 100° C., and the feed rate is 3ml / min to obtain spray-dried powder 35 gram, is the powdery anti-radiation Chinese medicine composition of the present invention.

Embodiment 3

[0030] Preparation of traditional Chinese medicine composition for radiation protection

[0031] (1) Weigh 250 grams of white plum, 300 grams of weeping grass, 300 grams of geranium, 300 grams of ramie root and 300 grams of saponin thorn, mix and add 10 times the total weight of the above-mentioned traditional Chinese medicine raw materials, soak in water for 3 hours, heat and fry Boil for 3 hours, filter; the dregs are added with water 8 times the total weight of each traditional Chinese medicine raw material, heated and decocted for 2 hours, filtered, the filtrates are combined, and the supernatant is obtained after standing to separate the solids;

[0032] (2) When the supernatant is concentrated to a relative density of 1.06, it is sent into a spray dryer for spray drying, the air inlet temperature is controlled at 160°C, the outlet temperature is 110°C, and the feed rate is 6ml / min to obtain spray-dried powder 100 gram, is the powdery anti-radiation Chinese medicine compo...

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Abstract

The invention belongs to the field of traditional Chinese medicine, and discloses a radiation-proof traditional Chinese medicinal composition and a preparation method and an application thereof. The traditional Chinese medicinal composition is made of the following raw materials in part by weight: 5 to 25 parts of salted and dried plum, 5 to 30 parts of stringy stonecrop, 5 to 30 parts of meadow cranesbill, 5 to 30 parts of radix boehmeriae and 5 to 30 parts of spina gleditsiae; after the raw materials are mixed, water with volume being 8 to 10 times of the general weight of the raw materials is added to immerse the mixed raw materials for 2 to 3 hours, the immersed raw materials are filtered after being heated and boiled, then water with the volume being 8 to 10 times of the general weight of the raw materials is added to heat and boil, then the immersed raw materials are filtered, the filtered liquid is combined to obtain the radiation-proof traditional Chinese medicinal composition, the radiation-proof traditional Chinese medicinal composition is statically placed, and upper clear liquid with solids being separated is concentrated, atomized and dried to obtain powdered traditional Chinese medicinal composition. The traditional Chinese medicinal composition can improve situation of white cell reduction caused by the radiation harm on organisms, can realize an effect on protection against the radiation, and is suitable for being taken by people working in a radiation environment for a long time and patients before or after tumor radiography.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition with anti-radiation effect and its preparation method and application. technical background [0002] With the development of social technology, various factors that produce radiation have been increasing. From the beginning of the last century to the present, radiation has penetrated into all areas of social life. In daily life, mobile phones and computers are gradually becoming necessities for human life and work; in the medical field, radiological diagnosis and treatment are widely used, such as radiological X-ray diagnosis, CT diagnosis, etc.; radiotherapy has become one of the three traditional methods for treating malignant tumors 1. Radiation therapy is the use of X-rays of different energies, electron rays, neutron rays, proton rays and γ-rays released by radioactive sources (such as 60 cobalt therapy machi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/736A61P39/00
Inventor 蔡宇张荣华
Owner JINAN UNIVERSITY
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