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Application of alkaloid component composition to preparation of medicament for resisting influenza A H1N1 virus

A technology of alkaloids and influenza virus, applied in the field of medicine, can solve problems such as influenza A H1N1 virus that has not yet been seen, and achieve the effect of abundant raw materials and easy production

Inactive Publication Date: 2012-04-18
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the use of the two types of compounds in the medical field has gradually attracted attention, and they have potential prospects for new drug development. However, there have been no relevant reports on the application of these two types of compounds to influenza A (H1N1) viruses.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] In the specific implementation of the present invention, the weight ratio of the 1-carbocarboline-β-carboline and 1-deoxymannojirimycin is 1:5, which is effectively used for preparing the medicine for preventing and treating influenza A (H1N1).

Embodiment 2

[0012] In the specific implementation of the present invention, the weight ratio of the 1-carbocarboline-β-carboline and 1-deoxymannoshirimycin is 5:1, which is effectively used for the preparation of drugs for preventing and treating Influenza A (H1N1).

Embodiment 3

[0014] In the specific implementation of the present invention, the weight ratio of 1-carbocarboline-β-carboline and 1-deoxymannoshirimycin is 2:4, which is effectively used to prepare the medicine for preventing and treating influenza A (H1N1).

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PUM

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Abstract

The invention relates to application of an alkaloid component composition to preparation of medicaments for resisting influenza A H1N1 virus and can effectively solve a problem of preparation of medicament for resisting influenza A H1N1 virus and controlling H1N1 influenza. A technical scheme is as below: The composition is prepared by mixing 1-carbomethoxy-belta-carboline and 1-deoxymannojirimycin in a mass ratio of 1-5:1-5 and can be effectively used in preparation of medicaments for treating and preventing influenza A H1N1, so as to realize application of the composition to preparation of medicaments for controlling influenza A H1N1. The composition of the invention is simple, can be produced easily from abundant raw materials and effectively applied to preparation of medicaments for treating and preventing influenza A H1N1, so as to solve a problem of drug administration for controlling influenza A H1N1; therefore, the invention is an innovation in medicaments for controlling influenza A H1N1.

Description

technical field [0001] The invention relates to the field of medicine, in particular to the application of an alkaloid component composition in the preparation of anti-influenza A (H1N1) virus medicine. Background technique [0002] Influenza A (H1N1) virus [Influenza A (H1N1) virus] is one of the most common influenza viruses infecting humans. It is easy to mutate, highly contagious, spreads quickly, and has high morbidity and mortality. There have been several global pandemics since the 19th century, the most recent being the H1N1 epidemic that broke out in Mexico in 2009. [0003] Currently, oseltamivir phosphate, the trade name of which is Tamiflu, is mainly recommended as an anti-influenza A (H1N1) virus drug. Tamiflu is a neuraminidase inhibitor, which inhibits the spread of the virus in the human body, especially the respiratory system, by inhibiting the activity of neuraminidase, thereby blocking the viral infection cycle process. Tamiflu can reduce the virus sprea...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/445A61K31/437A61P31/16
Inventor 张国斌邴飞虹田连起李朋伟张宾李寒冰吴宿慧栗俞程
Owner HENAN UNIV OF CHINESE MEDICINE
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