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Medicinal preparation with antitubercular effect and preparation method thereof

A pharmaceutical preparation and anti-tuberculosis technology, which are applied in the field of pharmaceutical preparations with anti-tuberculosis effects and the preparation thereof, can solve the problems of long taking time, damage, large side effects and the like, and achieve the effects of less toxic and side effects, special potency, and less taste.

Inactive Publication Date: 2012-07-11
NANJING TONGRENTANG PHARM CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the treatment of anti-tuberculosis, commonly used clinical drugs include isoniazid, rifampicin, streptomycin, pyrazinamide, ethambutol, etc., but these drugs have relatively large side effects, and take them for a long time. Taking these anti-tuberculosis drugs will cause different degrees of damage to the patient's body

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0022] The beneficial effect of the pharmaceutical preparation of the present invention will be further described through test examples below, and these test examples include pharmacodynamic tests and clinical curative effect observation tests.

[0023] The raw material drug chamaejamas used in the pharmaceutical preparation of the present invention is commercially available. Standard source: the 2010 edition of "Chinese Pharmacopoeia".

[0024] The oral preparation auxiliary materials used in the pharmaceutical preparation of the present invention are all commercially available and meet the standards under the relevant items of the Pharmacopoeia.

[0025] 1. The preclinical pharmacodynamics research results of the pharmaceutical preparation of the present invention: the in vitro anti-tuberculosis test shows that the pharmaceutical preparation of the present invention has obvious antibacterial effect on the human tubercle bacillus H37Rv strain, and the MIC is 500ug / ml. The ob...

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Abstract

The invention relates to a medicinal preparation with an antitubercular effect and a preparation method thereof. According to the medicinal preparation, a Chinese herbal medicine is Chinese wolfsbane root. The medicinal preparation is mainly used for treating various types of pulmonary tuberculosis, also can be used for treating other tuberculosis diseases, and is suitable for patients who are allergic to antitubercular agents and tolerant to medicines and suffer from tuberculosis combined with hepatopathy. The medicinal preparation is prepared from a few medicines, special in medicinal efficacy, safe and effective and can be prepared into various oral preparations, and compared with western antitubercular medicines, the medicinal preparation has the advantage of small toxic and side effects.

Description

technical field [0001] The invention relates to a pharmaceutical preparation with anti-tuberculosis effect derived from traditional Chinese medicine and a preparation method thereof. Background technique [0002] Tuberculosis is a common disease that seriously affects people's health. The current tuberculosis has been greatly reduced with the development of modern medicine, but the number is still not small in terms of the whole city, the whole province, and the whole country. At present, the tuberculosis epidemic is still very serious in our country. In the population, one in every 150 people suffers from TB. According to the second national tuberculosis sampling survey, there are currently 5.7 million tuberculosis patients in the country. In recent years, the prevalence rate has declined slowly, and some provinces and cities still have an upward trend. Although there are some anti-tuberculosis drugs in Western medicine, after long-term clinical use, quite a few cases hav...

Claims

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Application Information

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IPC IPC(8): A61K36/47A61P31/06
Inventor 陈家进王业盈苏娟徐菁
Owner NANJING TONGRENTANG PHARM CO LTD
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