Chinese medicinal solid preparation and indications thereof

A technology of solid preparations and traditional Chinese medicine, applied in the field of medicine, can solve problems such as slow treatment, incomplete treatment, easy damage to the liver and kidneys, etc.

Inactive Publication Date: 2012-07-11
HAINAN MEILAN SMITH KLINE PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The clinical prevention and treatment of hand, foot and mouth disease and exogenous diseases mostly use anti-virus, cooling and symptomatic treatment, and some hormones are also used. The therapeutic effect has certain limitations, the scope of application is small, and it cannot remove the damp heat and detoxification in the body. Treat the symptoms but not the root cause, easy to relapse, and incomplete treatment. After long-term use of western medicine, it is easy to damage the liver and kidneys, and even produce some serious adverse reactions, and the treatment is slow, which makes clinical drug safety hidden dangers.

Method used

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  • Chinese medicinal solid preparation and indications thereof
  • Chinese medicinal solid preparation and indications thereof
  • Chinese medicinal solid preparation and indications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] Example 1 tablet

[0055] Prescription composition:

[0056] Honeysuckle 250g, Forsythia 350g, Ageratum 160g, Artemisia argyi 130g, Mint 70g, Comfrey 240g, Raw licorice 130g, Starch 200g, Mannitol 50g, Low-substituted hydroxypropyl cellulose 10g, Tween 80 10g, Polyethylene glycol 4000 5g.

[0057] Preparation:

[0058] (1) Weigh the Qiwei traditional Chinese medicine in the above prescription according to the weight components, add water to decoct and distill for three times, add 15L of water for the first time to soak for 60 minutes, decoct and distill for 1.5 hours; add 13L for the second and third times respectively Decoct water and distill for 1 hour; collect volatile oil at the same time and set aside;

[0059] (2) The decoctions were combined and filtered, and the filtrate was concentrated to a relative density of about 1.12 (60°C) to obtain 960ml of concentrated solution;

[0060] (3) Add 1740ml of ethanol to the above-mentioned concentrated solution, let ...

Embodiment 2

[0063] Example 2 Dispersible tablets

[0064] Prescription composition:

[0065] Honeysuckle 350g, Forsythia 250g, Ageratum 240g, Artemisia argyi 70g, Mint 130g, Comfrey 160g, Raw licorice 70g, Mannitol 300g, Low-substituted hydroxypropyl cellulose 20g, Crospovidone 10g, Tween 80 10g, Polymer Ethylene glycol 4000 5g.

[0066] Preparation:

[0067] (1) Weigh the Qiwei traditional Chinese medicine in the above prescription according to the weight components, add water to decoct and distill for three times, add 15L of water for the first time to soak for 60 minutes, decoct and distill for 1.5 hours; add 13L for the second and third times respectively Decoct water and distill for 1 hour; collect volatile oil at the same time and set aside;

[0068] (2) The decoctions were combined and filtered, and the filtrate was concentrated to a relative density of about 1.12 (60°C) to obtain 960ml of concentrated solution;

[0069] (3) Add 1740ml of ethanol to the above-mentioned conce...

Embodiment 3

[0072] Example 3 Capsules

[0073] Prescription composition:

[0074] Honeysuckle 300g, Forsythia 300g, Ageratum 200g, Artemisia argyi 100g, Mint 100g, Comfrey 200g, Raw licorice 100g, Starch 200g, Mannitol 30g, Low-substituted hydroxypropyl cellulose 20g, Tween 80 10g, Polyethylene glycol 4000 10g.

[0075] Preparation:

[0076] (1) Weigh the Qiwei traditional Chinese medicine in the above prescription according to the weight components, add water to decoct and distill for three times, add 15L of water for the first time to soak for 60 minutes, decoct and distill for 1.5 hours; add 13L for the second and third times respectively Decoct water and distill for 1 hour; collect volatile oil at the same time and set aside;

[0077] (2) The decoctions were combined and filtered, and the filtrate was concentrated to a relative density of about 1.10 (60°C) to obtain 1020ml of a concentrated solution;

[0078] (3) Add 1800ml of ethanol to the above-mentioned concentrated solutio...

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PUM

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Abstract

The invention discloses a Chinese medicinal preparation which is suitable for preventing hand-foot-and-mouth disease and external infection diseases and treating sub-clinical diseases. The Chinese medicinal preparation consists of honeysuckle flower, weeping forsythia, wrinkled gianthyssop herb, argy wormwood leaf, mint, Sinkiang arnebia root and raw liquoric root and is prepared by a scientific processing process. By clinical demonstration, the Chinese medicinal preparation is used for preventing and treating the hand-foot-and-mouth disease and the external infection diseases, which are caused by exogenous evil according to the theory of traditional Chinese medical science. The Chinese medicinal preparation has an obvious inhibiting effect on staphylococcus aureus, hemolytic streptococcus, dysentery, typhoid fever, diplococcus meningitides, diplococcus pneumoniae, pyocyanosis, influenza virus and the like.

Description

technical field [0001] The invention relates to a solid preparation of traditional Chinese medicine, in particular to a solid preparation of traditional Chinese medicine used for the prevention or treatment of hand-foot-mouth disease and exogenous diseases, as well as its preparation method and indications, belonging to the technical field of medicine. Background technique [0002] According to TCM theory, the main syndromes of exogenous pathogenic factors are lung-defense evil, damp-evil trapping the spleen, intestinal damp-heat, evil origin in Shaoyang, lung-heat syndrome, gallbladder heat syndrome, stomach-heat syndrome, fu-organ excess syndrome, and bladder heat syndrome. The common features of these syndromes are seasonality, acute onset, and short course of disease, all of which are syndromes caused by exogenous pathogens attacking the exterior, exogenous pathogens interfering with the interior, and exogenous pathogenic attachments causing dysfunction of the correspondi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/634A61P31/04A61P31/16A61P31/14A61P11/00A61P11/04A61P1/12A61P29/00
CPCY02A50/30
Inventor 杨明贵张致家曹丽梅
Owner HAINAN MEILAN SMITH KLINE PHARMA
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