Application of dendrobium candidum in preparing medicines for treating immune chronic gastritis

A technology of Dendrobium officinale and chronic gastritis is applied in a new application field to achieve the effects of good safety, reducing gastric mucosal atrophy and consolidating curative effect

Active Publication Date: 2012-07-11
ZHEJIANG TIANHUANG MEDICINAL PLANT PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no medicine in the existing Chinese patent medicines that is suitable for immune chronic gastritis to regulate the spleen and stomach, take a long course of treatment, and promote the recovery of pathological changes.

Method used

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  • Application of dendrobium candidum in preparing medicines for treating immune chronic gastritis
  • Application of dendrobium candidum in preparing medicines for treating immune chronic gastritis
  • Application of dendrobium candidum in preparing medicines for treating immune chronic gastritis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] [Example 1] Preparation of Tiepi Fengdou Granules

[0022] (1) Weigh 167g of Tiepi Fengdou and 133g of American ginseng according to the prescription ratio, and set aside.

[0023] (2) Soak Tiepi Fengdou medicinal material in warm water for half an hour, heat extraction 3 times, 8 hours each time. After each extraction, the extract was centrifuged and filtered, and the filtrates were combined three times to obtain the extract. The extract was concentrated under reduced pressure to a concentrated solution with a relative density of 1.00 (55° C.) and set aside.

[0024] (3) Put the American ginseng in a multi-functional extraction tank, reflux extraction with 70% ethanol for 3 times, each time for 3 hours, combine the extracts, recover ethanol under reduced pressure, concentrate under reduced pressure to a concentrated solution with a relative density of 1.05 (90°C) ,spare.

[0025] (4) Combine the above-mentioned Tiepi Fengdou extract concentrate and American ginseng ...

Embodiment 2

[0026] [Example 2] Preparation of Tiepi Fengdou Granules

[0027] (1) Weigh 120g of Tiepi Fengdou and 180g of American ginseng according to the prescription ratio, and set aside.

[0028] (2) Soak Tiepi Fengdou medicinal material in warm water for half an hour, heat extraction 3 times, 8 hours each time. After each extraction, the extract was centrifuged and filtered, and the filtrates were combined three times to obtain the extract. The extract was concentrated under reduced pressure to a concentrated solution with a relative density of 1.20 (45°C) and set aside.

[0029] (3) Put the American ginseng in a multi-functional extraction tank, reflux extraction with 70% ethanol for 3 times, each time for 3 hours, combine the extracts, recover the ethanol under reduced pressure, concentrate under reduced pressure to a concentrated solution with a relative density of 1.25 (80°C) ,spare.

[0030] (4) Combine the above-mentioned Tiepi Fengdou extract concentrate and American ginsen...

Embodiment 3

[0031] [Example 3] Preparation of Tiepi Fengdou Granules

[0032] (1) Weigh 180g of Tiepi Fengdou and 120g of American ginseng according to the prescription ratio, and set aside.

[0033] (2) Soak Tiepi Fengdou medicinal material in warm water for half an hour, heat extraction 3 times, 8 hours each time. After each extraction, the extract was centrifuged and filtered, and the filtrates were combined three times to obtain the extract. The extract was concentrated under reduced pressure to a concentrated solution with a relative density of 1.13 (48°C) and set aside.

[0034] (3) Put the American ginseng in a multi-functional extraction tank, reflux and extract with 70% ethanol for 3 times, each time for 3 hours, combine the extracts, recover the ethanol under reduced pressure, concentrate under reduced pressure to a concentrated solution with a relative density of 1.12 (85°C) ,spare.

[0035] (4) Combine the above-mentioned Tiepi Fengdou extract concentrate and American ginse...

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Abstract

The invention, relating to a novel application of dendrobium candidum, aims at providing an application of dendrobium candidum in preparing medicines for treating immune chronic gastritis. The invention discloses the application of dendrobium candidum in preparing medicines for treating immune chronic gastritis, and a preparation method of medicines for treating immune chronic gastritis based on dendrobium candidum. The invention provides a novel means for treating immune chronic gastritis. According to the invention, the effects of mitigating body weight loss, mitigating gastric mucosal inflammation, hyperaemia, hemorrhage and erosion, decreasing mortality ratio, and mitigating atrophy of gastric mucous are achieved. The dendrobium candidum wall.ex lindl drop(DCWD) disclosed herein has mild formula, is suitable for conditioning and rehabilitation of spleen and stomach diseases with excess and deficiency syndromes due to spleen-stomach deficiency or sthenia symptoms caused by asthenia. The treatment of Chinese medicines has good safety. The Chinese medicines can be taken for a long time, and has the combined actions of consolidating curative effect, preventing a recurrence and adjusting the whole body.

Description

technical field [0001] The invention relates to a new application of dendrobium candidum, in particular to the application of dendrobium candidum in preparing medicine for treating immune chronic gastritis. Background technique [0002] In the "Sydney System-New Gastritis Classification Method" proposed by the Ninth World Congress of Gastroenterology in Sydney (August 1990), gastritis is divided into three categories according to pathological forms: acute, chronic and specific. The etiology includes pylorus Helicobacter, autoimmune, drug and idiopathic etc. [0003] The type of autoimmune chronic (atrophic) gastritis is found in: "Classification of Chronic Gastritis According to Location, Morphology, and Etiology" proposed by the Houston Gastritis Symposium (September 1994), which divides chronic gastritis into: Atrophic, atrophic (autoimmune, multifocal atrophic), special forms (chemical, radioactive, lymphocytic, noninfectious, granulomatous, eosinophilic, other infectiou...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61P1/04
Inventor 吴人照陈立钻杨兵勋戴关海陈宇楼正家杨芳亮张旭峰陈武兵张春丽杨敏童晔玲杨锋李珺张根花郑纯威李端阳
Owner ZHEJIANG TIANHUANG MEDICINAL PLANT PHARMA
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