Cell printing self-adaptive inkjet driving control method

A cell printing and self-adaptive technology, applied in tissue cell/virus culture devices, printing devices, biochemical equipment and methods, etc., can solve nozzle clogging, difficulty in ejecting high-viscosity and high-density liquids, and hinder cell Problems such as the realization of printing projects, to achieve the effect of avoiding clogging

Inactive Publication Date: 2012-07-11
XIDIAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of the cell printing is to load the cultured cells in a clean ink cartridge and use a commercial nozzle to spray. Since this type of nozzle is designed for jetting ink, there are two main problems when spraying biological agents with

Method used

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  • Cell printing self-adaptive inkjet driving control method
  • Cell printing self-adaptive inkjet driving control method
  • Cell printing self-adaptive inkjet driving control method

Examples

Experimental program
Comparison scheme
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Example Embodiment

[0064] The specific results and working principle of the piezoelectric nozzle:

[0065] (1) The specific structure of the piezoelectric nozzle

[0066] Reference figure 2 The shown schematic diagram of the structure of the piezoelectric nozzle includes an inkjet liquid box, an inkjet channel, a nozzle hole and a piezoelectric sheet. The electric sheets and piezoelectric sheets are distributed above and below the ink jet channel.

[0067] (2) Working principle of piezoelectric nozzle

[0068] Reference figure 1 , At t 0 At the moment, the driver applies a square wave signal with a width of T0 to the piezoelectric film. The voltage causes the piezoelectric film to shrink, forming a negative pressure in the inkjet channel chamber, and the negative pressure propagates toward the inkjet liquid tank (b); At the inkjet liquid tank, because the inkjet liquid tank is infinite, the negative pressure wave will be completely reflected as a positive pressure wave (c); when the positive pressure...

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PUM

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Abstract

The invention belongs to the field of the tissue engineering, and particularly discloses a cell printing self-adaptive inkjet driving control method in which a piezo printhead is used for controlling. The self-adaptive inkjet driving control method is characterized in that an inkjet liquid tank, an inkjet passage, a spray orifice and piezoelectric plates are adopted; one end of the inkjet passageis communicated to the spray orifice and the other end of the inkjet passage is communicated with the inkjet liquid tank; the piezoelectric plates are arranged outside the inkjet passage; and the piezoelectric plates are distributed on and under the inkjet passage. The cell printing self-adaptive inkjet driving control method is used for implementing the jetting of a high-viscosity biological agent and for solving the phenomenon of blocking.

Description

technical field [0001] The invention belongs to the field of tissue engineering, and specifically relates to an adaptive inkjet drive control method for cell printing controlled by a micro piezoelectric nozzle, which is used to realize the injection of high-viscosity biological preparations and solve the clogging phenomenon. Background technique [0002] As a new technology to replace the traditional biodegradable solid scaffold method, cell printing has great development potential in tissue engineering. It uses the principle that cells can self-assemble in developmental biology, just like embryonic tissue forms a functional structure, and a three-dimensional tissue structure can be formed by printing cells layer by layer. Compared with cell shaping based on three-dimensional porous scaffolds, cell printing is computer-assisted, not just relying on the adhesion, proliferation, and differentiation of cells. The paper "Delivery of Human Fibroblast Cells by Piezoelectric Drop-...

Claims

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Application Information

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IPC IPC(8): B41J29/393B41J2/01B41J3/00C12M3/00
Inventor 黄进胡飞飞徐荣泽范建宇
Owner XIDIAN UNIV
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