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Novel method for detecting platelet aggregation ability

A technology for platelet aggregation and detection methods, which is used in measurement devices, individual particle analysis, scientific instruments, etc., can solve the problems of cumbersome detection operations, not widely used in clinical detection, and poor accuracy of results, and achieves less influencing factors and reliable detection results. , the effect of convenient detection

Inactive Publication Date: 2012-07-11
SINNOWA MEDICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, there are detection methods such as whole blood resistance method and microscope counting, but these methods have poor accuracy and cumbersome detection operations, and have not been widely used in clinical detection.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0006] During the test, the same blood sample was divided into two parts, one blood sample was not added with platelet aggregation inducing agent, and the other blood sample was treated with aggregation inducing agent, and then the number of platelets and Finally, by comparing the number and volume (size) of platelets obtained from the two blood samples, the aggregation of platelets under the action of the aggregation inducer can be measured, and the aggregation ability of the platelets in the blood sample can be calculated.

Embodiment 2

[0008] During the detection, the same blood sample was divided into two parts, one blood sample was not added with platelet aggregation inducing agent, and the other blood sample was treated with aggregation inducing agent, and then the two blood samples were detected by the electrical impedance method detector, and finally the obtained The parameters such as mean platelet volume (MPV), platelet specific volume (PCT) or platelet volume distribution width (PDW) of the two blood samples were compared to calculate the aggregation ability of platelets in the blood sample.

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Abstract

The invention relates to a novel method for detecting platelet aggregation ability, belonging to the field of clinical laboratory medicine. The method uses an impedance technology detecting instrument which can simultaneously count platelets and measure the particle volume (size) of the platelets to directly detect the platelet aggregation ability of whole blood samples, and plasma is not separated. During detection, one blood sample is divided into two parts, one part of blood sample is directly detected without adding a platelet aggregation inducer, the other part of blood sample is detected after adding the platelet aggregation inducer to carry out induction treatment, and finally the two obtained detecting results as basic data are compared to calculate the platelet aggregation ability.

Description

1. Technical field [0001] The invention relates to a new detection method of platelet aggregation ability, which belongs to the field of clinical laboratory medicine. 2. Background technology [0002] Platelet aggregation ability (or aggregation rate) is an important function of platelets. The existing detection method is mainly to add an aggregation-inducing agent to the isolated platelet-rich plasma to cause the platelets to aggregate. After the platelets aggregate, the plasma turbidity changes, and the photoelectric turbidity method is used to detect the turbidity change to obtain the result. In addition, there are detection methods such as whole blood electrical resistance method and microscope counting, but these methods have poor accuracy and cumbersome detection operations, and have not been widely used in clinical detection. 3. Contents of the invention [0003] A new detection method of platelet aggregation ability is carried out by using an electrical impedance ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N15/10
Inventor 徐新曹宁董自权
Owner SINNOWA MEDICAL SCI & TECH
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