Analyzer and analyzing method

An analysis device and analysis method technology, which is applied in the direction of analysis materials, measuring devices, chemical instruments and methods, etc., can solve the problem of limited degree of freedom in the structure of the device, and achieve the effect of improving the degree of freedom in the structure

Active Publication Date: 2012-07-25
SYSMEX CORP
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Problems solved by technology

[0004] However, in the analysis device disclosed in the above-mentioned Japanese Patent Laid-Open (Japanese Patent Laid-Open) No. 2001-91521, in order to prevent the re-diffusion of the magnetic particles captured in advance on the inner surface of the container, in the adopted structure, it is necessar...

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Embodiment Construction

[0054] Specific embodiments of the present invention will be described below based on the drawings.

[0055] First, refer to Figure 1 to Figure 9 , the configuration of the immunoassay device 1 according to one embodiment of the present invention will be described.

[0056] The immunoassay device 1 according to one embodiment of the present invention is a device for quantitatively or qualitatively measuring an antigen or antibody contained in a sample (blood sample) such as blood. In this immunoassay device 1, the magnetic particle (R2 reagent) is first bound to the capture antibody (R1 reagent) bound to the antigen contained in the sample (serum), and then the magnetic capture binding (Bound, binding) of the BF separation unit 11 is used once. After the complex of antigen, capture antibody and magnetic particles, remove the R1 reagent containing unreacted (Free, free) capture antibody at the same time (that is, BF separation). Then, after the immunoassay device 1 binds the...

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Abstract

The present invention is an analyzer for analyzing a target substance contained in a sample using a reagent containing magnetic particles, the analyzer comprising: a magnetic capturing section that comprises a first holder configured to hold a container accommodating a liquid specimen containing a sample and the reagent containing the magnetic particles and that comprises a first magnetic force generating member configured to magnetically capture the magnetic particles in the container held by the first holder; a target substance separating section that comprises a second holder configured to hold the container and a second magnetic force generating member configured to magnetically capture the magnetic particles in the container held by the second holder, and that discharges a cleaning liquid into the container held by the second holder and aspirates a liquid in the container held by the second holder while magnetically capturing the magnetic particles in the container with the second magnetic force generating member; and a container transferring section configured to transfer the container from the magnetic capturing section to the target substance separating section, wherein the first magnetic force generating member of the magnetic capturing section is arranged on a lower side of the container held by the first holder and is configured to magnetically capture the magnetic particles in the container held by the first holder. The present invention is also to present an analyzing method for analyzing a target substance contained in a sample using a reagent containing magnetic particles.

Description

Technical field: [0001] The invention relates to an analysis device and an analysis method, in particular to an analysis device and an analysis method for analyzing a target substance contained in a sample with a reagent containing magnetic particles. Background technique: [0002] There is known an analysis device for analyzing a target substance contained in a sample using a reagent containing magnetic particles (for example, refer to Japanese Patent Laid-Open (Japanese Patent Laid-Open) No. 2001-91521). This analysis device performs BF (Bound-Free) separation processing to separate the immune complex containing the target substance from the unreacted substance. In the BF separation process, the immune complex generated by the reaction of the analyte (antigen or antibody) in the sample with magnetic particles is captured to the inner wall of the reaction vessel by magnetic force, wherein the magnetic particle binds the reaction specifically bound to the analyte Inject the...

Claims

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Application Information

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IPC IPC(8): G01N33/543G01N35/02
CPCG01N27/745B03C1/01B03C1/0332B03C1/288B03C2201/18B03C2201/26G01N35/0098
Inventor 丰屿弘人元津和典
Owner SYSMEX CORP
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