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Extraction and separation method of harringtonine

A technology of harringtonine and separation method, which is applied in the field of extraction and separation of harringtonine, and can solve problems such as unstable output of harringtonine

Inactive Publication Date: 2012-08-15
GUIZHOU BOFENG BIOLOGICAL TECH IND DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since the planting and cultivation of Chinese cloverleaf is still in its infancy, the extraction of harringtonine from the branches and leaves of cloverleaf is even rarer, and there is no mature extraction method at present. , the output of harringtonine is extremely unstable, so it is an urgent problem to study a set of extraction and separation methods for harringtonine that can increase the output of harringtonine and have a stable output

Method used

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Embodiment Construction

[0014] Cedarwood is a kind of subtropical medicinal plant. Due to overexploitation, the number of resources has decreased sharply, and it is in an endangered state. And because the clover is a wild plant, the growth environment is complicated, and it is very difficult to grow, but the harringtonine (also known as long-stalked cypress, molecular formula C) extracted from the branches and leaves of the clover 28 h 37 o 9 N) is a specific drug for the treatment of acute leukemia and malignant lymphoma, and also has good curative effects on melanoma, lung cancer, breast cancer and brain tumors, so the present invention is specially aimed at the extraction and separation of harringtonine. Through research and experiments, a complete set of extraction and separation methods for harringtonine has been obtained.

[0015] A kind of extraction and separation method of harringtonine of the present invention, its concrete steps are:

[0016] a) First, cut the branches and leaves of Chi...

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PUM

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Abstract

The invention relates to an extraction and separation method of harringtonine. The method comprises the following steps of: sequentially performing drying, crushing, extraction, concentration, separation and the like on raw materials so as to finally get harringtonine crystals, and the purity of the harringtonine is 96.4%. The harringtonine obtained by adopting the extraction and separation method of the harringtonine has the advantages of high yield and stable yield, and the yield is 0.298%. The extraction and separation method of the harringtonine technically provides an effective guarantee and makes a great contribution for development of the cephalotaxus fortunei industry in the field of medicines.

Description

technical field [0001] The invention relates to a method for extracting and separating harringtonine. Background technique [0002] The three-pointed fir is a precious tree species. It is an evergreen tree with ochre-brown skin that falls off in flakes. The small branches are opposite and the bud scales are persistent at the base. The humid mountain streams are distributed in southern Shaanxi, southern Gansu, East China, South China, and Southwest China. Growing in sparse forests on hillsides, in moist and well-drained valleys. Phytoalkaloids extracted from cloverleaf have certain curative effect on cancer treatment. In addition, because its wood is firm, elastic, and has multiple uses, the oil extracted from the seeds can be used for making soap and paint, and the fruit is used as medicine to moisturize the lungs, relieve cough, and eliminate stagnation. Wild economic plants have many protection values. [0003] In the field of medicine, harringtonine and homoharrington...

Claims

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Application Information

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IPC IPC(8): C07D491/20
Inventor 陈良韩碧维余家奇
Owner GUIZHOU BOFENG BIOLOGICAL TECH IND DEV
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