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Device used for rat brain tissue slicing and layering

A tissue slicing and slicing technology, which is applied in the direction of sampling devices, etc., can solve the problems of operator inconvenience, accidental injury to experimenters, single slicing direction, etc., and achieve the effect of ensuring the quality of slicing, reducing the cost of experiments, and not easy to break

Inactive Publication Date: 2013-11-06
THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, with the continuous development of the field of basic medical research, the research of animal histology has gradually developed to a deeper level, and the requirements for the accuracy of tissue positioning are getting higher and higher. In recent years, especially the research on brain tissue of experimental animals has gained more However, due to the complex anatomical structure of animal brain tissue, various functional areas, and high sensitivity, it brings a lot of inconvenience to the research work, especially the observation and research of fresh brain tissue is even more difficult.
For example, the positioning and separation of deep nuclei in fresh brain tissue are widely used in modern medical research. In the past, the separation method was single, mainly for the experimental animal brain slice module sold in the market. This module can separate the required tissues inside the rat brain. However, there are the following problems in actual operation: (1) the module can only fix the mouse brain, but there is no matching fixed blade frame, and the experimenter is often accidentally injured during the operation, which brings a lot of inconvenience to the operator; (2) the mouse brain It is difficult to locate inside the tissue, and it is difficult to accurately separate the tissue at the required level; (3) The module slices in a single direction, and slices in different directions require different modules, and a single module is expensive, which increases the cost of experiments; ( 4) In the actual operation process, the two blades cannot cut to the bottom of the tissue at the same time. Since the two blades cannot be operated synchronously, the positioning of the mouse brain slices is inaccurate and easily damaged, and it is difficult to ensure the quality of the slices.

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  • Device used for rat brain tissue slicing and layering

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Embodiment Construction

[0018] see figure 1 , The present invention's device for slicing and delaminating rat brain tissue includes: an operating table 5, on which a concave cavity 7 is arranged. The slicing module 3 is provided with a plurality of equally spaced sipes 13, the slits 13 can be arranged horizontally or vertically (two moulds), and the slicing modules with different arrangements of sipes can be replaced as required for actual slicing.

[0019] During the slicing operation, put the fresh mouse brain tissue 2 on the slicing module, and embed the slicing module in the cavity 7. Two fastening screws 4 are provided on the back of the console to extend into the cavity 7 just to fix the slicing module 3 in the cavity 7. In the rectangular recess of the worktop.

[0020] The front of the console is provided with a dovetail groove 6 and a rack 8 along the length direction. The dovetail groove is matched with a dovetail track. The dovetail track is fixedly connected with an angle steel 11 parall...

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Abstract

The invention discloses a device used for rat brain tissue slicing and layering. The device comprises a slicing module, wherein the slicing module is provided with a plurality of cutter grooves with equal spacing, and fresh rat brain tissues are placed on the slicing module in slicing operation. The device is characterized in that the slicing module is embedded in a rectangular cavity on an operation desk, a cutter with a tool rest is arranged above the slicing module, two blades which are mutually parallel and vertical downwards are arranged below the tool rest, spacing between the two blades is just equal to distance between two cutter grooves of the slicing module, the cutter is connected with the upper end of a vertical arm, and the lower end of the vertical arm is connected with a mechanism which can move along the front length direction of the operation desk for positioning.

Description

technical field [0001] The invention relates to a slicing device for animal brain tissue in medical scientific research, in particular to a slicing device capable of accurately and quickly obtaining different levels of mouse brain tissue. Background technique [0002] At present, with the continuous development of the field of basic medical research, the research of animal histology has gradually developed to a deeper level, and the requirements for the accuracy of tissue positioning are getting higher and higher. In recent years, especially the research on brain tissue of experimental animals has gained more However, due to the complex anatomical structure of animal brain tissue, various functional areas, and high sensitivity, it brings a lot of inconvenience to the research work, especially the observation and research of fresh brain tissue is even more difficult. For example, the positioning and separation of deep nuclei in fresh brain tissue are widely used in modern med...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N1/06
Inventor 申新赵鸽刘养凤方伟赵海康张妍春陈孛玉马赛田爽张学策南海燕
Owner THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV
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