Tourmaline/chitosan hydrochloride compound spray-type aqueous dressing and preparation method thereof

A technology of chitosan hydrochloride and tourmaline, which is applied in the fields of medical science, bandages, absorbent pads, etc., can solve the problems such as research reports on water dressings compounded by chitosan hydrochloride and tourmaline, etc. The effect of promoting wound healing, good film formation and convenient use

Inactive Publication Date: 2012-09-19
CHENGDU UNIVERSITY OF TECHNOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] So far, there is no research report on the aqueous dressing compounded by chitosan hydrochloride and tourmaline

Method used

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  • Tourmaline/chitosan hydrochloride compound spray-type aqueous dressing and preparation method thereof
  • Tourmaline/chitosan hydrochloride compound spray-type aqueous dressing and preparation method thereof
  • Tourmaline/chitosan hydrochloride compound spray-type aqueous dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] (1) 2g chitosan hydrochloride is dissolved in 95.8g deionized water to obtain chitosan hydrochloride aqueous solution;

[0035] (2) Chitosan hydrochloride solution in (1) is added 0.2 g of tourmaline powder under 600 mesh sieves, mechanically stirred, and mixed uniformly;

[0036] (3) Add 2 g of PVP ethanol solution with a concentration of 50% to the mixed solution, mechanically stir, and mix uniformly to obtain tourmaline / chitosan hydrochloride composite spray-type aqueous wound dressing;

[0037] XRD spectrum see figure 1 ,from figure 1 It can be seen that the composite material of tourmaline / chitosan hydrochloride composite spray-on water wound dressing after smearing or spraying into a film does not contain other impurities, except for chitosan, tourmaline and a small amount of PVP, no other impurities exist.

[0038] IR Spectrum See figure 2 ,from figure 2 It can be seen that the addition of tourmaline and a small amount of PVP did not significantly change th...

Embodiment 2

[0043] (1) 1g chitosan hydrochloride is dissolved in 98.45g deionized water to obtain chitosan hydrochloride aqueous solution;

[0044] (2) Chitosan hydrochloride solution in (1) is added 0.05g of tourmaline powder under 600 mesh sieves, mechanically stirred, mixes;

[0045] (3) Add 0.5 g of PVP ethanol solution with a concentration of 50% to the mixed solution, mechanically stir, and mix uniformly to obtain tourmaline / chitosan hydrochloride composite spray-type aqueous wound dressing;

[0046] XRD spectrogram, IR spectrogram, SEM photograph, water vapor transmission rate are similar to embodiment 1.

[0047] The tourmaline / chitosan hydrochloride composite spraying type aqueous wound dressing that present embodiment obtains contains 1% chitosan hydrochloride, 0.05% tourmaline, 0.25% PVP and 0.25% ethanol, other ingredients It is deionized water, which has the functions of convenient use, fast film formation, small skin irritation, antibacterial and anti-inflammatory, coagulat...

Embodiment 3

[0049] (1) 5g chitosan hydrochloride is dissolved in 89g deionized water to obtain chitosan hydrochloride aqueous solution;

[0050] (2) Chitosan hydrochloride solution in (1) is added 1g of tourmaline powder under 600 mesh sieves, mechanically stirred, mixes;

[0051] (3) Add 5 g of PVP ethanol solution with a concentration of 50% to the mixed solution, mechanically stir, and mix uniformly to obtain tourmaline / chitosan hydrochloride composite spraying type water wound dressing;

[0052] XRD spectrogram, IR spectrogram, SEM photograph, water vapor transmission rate are similar to embodiment 1.

[0053] The tourmaline / chitosan hydrochloride composite spraying type aqueous wound dressing that present embodiment obtains contains 5% chitosan hydrochloride, 1% tourmaline, 2.5% PVP and 2.5% ethanol, other ingredients It is deionized water, which has the functions of convenient use, fast film formation, small skin irritation, antibacterial and anti-inflammatory, coagulation and hemo...

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Abstract

The invention relates to a tourmaline / chitosan hydrochloride compound spray-type aqueous dressing and belongs to the technical field of compound aqueous wound dressings. In order to solve the technical problems, the invention provides the compound spray-type aqueous dressing which is suitable for the field of the wound dressings. In the compound spray-type aqueous dressing provided by the invention, chitosan hydrochloride plays a role of blood coagulation and hemostasis, antibiosis antiphlogosis and film formation; tourmaline plays a role of launching far infrared rays, generating negative ions and promoting cell growth and wound healing; and polyvinylpyrrolidone (PVP) in a small number of PVP alcohol solution as an auxiliary material plays a role of a film-forming agent, a dispersing agent and a binding agent. The prepared compound spray-type aqueous dressing is convenient in use, slight in skin irritation and high in film-forming speed, has good effects of antibiosis antiphlogosis and blood coagulation and hemostasis, can be used for launching the far infrared rays, generating the negative ions and promoting the cell growth and the wound healing, is good in air permeability and moisture permeability after the film is formed and can be used as a biological wound dressing.

Description

technical field [0001] The invention relates to a tourmaline / chitosan hydrochloride composite spraying type water dressing, belonging to the technical field of composite water wound dressings. Background technique [0002] Wound dressings play a very important role in the current treatment or repair of skin injuries, but most of the commercialized wound dressings are in the form of patches or powders, which are inconvenient to use on large-area wounds and parts of the body. Liquid spray-type aqueous dressings have the advantages of being convenient to use, avoiding bandages, reducing pain for patients, and quickly forming films, etc., making them have broad application prospects in medical dressings. [0003] Chitosan hydrochloride is a chitosan derivative with good water solubility, which has good biocompatibility, bioadhesion and the effect of promoting drug absorption, and has antibacterial, anti-inflammatory, blood coagulation and hemostasis effects, and Good film-formi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/42A61L15/28A61L15/18
Inventor 李峻峰肖建刚余午曹莉清郭梅婷邱克辉赖雪飞张银
Owner CHENGDU UNIVERSITY OF TECHNOLOGY
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