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Medicine composition for treating xerophthalmia and preparation method and application thereof
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A composition and technology for dry eye, applied in the directions of drug combination, pharmaceutical formula, medical preparation containing active ingredients, etc., can solve problems such as high cost, unfavorable long-term use by patients, etc. Good economical effect
Active Publication Date: 2013-10-16
上海医药集团中药研究所有限公司
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Problems solved by technology
[0004] However, among the currently reported drugs for the treatment of dry eye syndrome, there are many medicinal materials in the prescription and the cost is high, which is not conducive to the long-term use of patients.
At present, there is no report on the treatment of dry eye syndrome with only the four herbs of Rhizoma Polygonatum, Radix Glycyrrhizae, Lycium barbarum, and Chrysanthemum.
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Embodiment 1
[0021] The preparation method of embodiment 1 pharmaceutical composition of the present invention
[0022] Take 15g of Rhizoma Polygonatum, 10g of Radix Ginseng, 10g of Fructus Lycii, and 10g of Chrysanthemum, add water to decoct, and combine the filtrates to obtain the pharmaceutical composition of the present invention.
Embodiment 2
[0023] Embodiment 2 The preparation method of pharmaceutical composition of the present invention
[0024] Take 12g of Rhizoma Polygonatum, 12g of Radix Glycyrrhizae, 12g of Lycium barbarum, and 12g of Chrysanthemum, add water to decoct, combine the filtrates, concentrate, dry, add appropriate amount of dextrin, and granulate to obtain the pharmaceutical composition granules of the present invention.
Embodiment 3
[0025] Embodiment 3 The preparation method of pharmaceutical composition of the present invention
[0026] Get 18g of sealwort, 8g of Radix Adenophora, 8g of medlar, and 8g of chrysanthemum, add water to decoct, combine the filtrate, concentrate, dry, add appropriate amount of microcrystalline cellulose, pack into capsules, and obtain the capsule of the pharmaceutical composition of the present invention.
[0027] The beneficial effects of the present invention will be specifically described below through test examples.
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Abstract
The invention discloses a medicine composition for treating xerophthalmia. The medicine composition is a preparation prepared from the following crude drugs in weight ratio: 12-18 parts of rhizoma polygonati, 8-12 parts of radix glehniae, 8-12 parts of medlar and 8-12 parts of chrysanthemum. According to the medicine composition disclosed by the invention, the rhizoma polygonati, the radix glehniae, the medlar and the chrysanthemum are reasonably combined, and thus, symptoms, such as dryness, foreign body sensation and hyperemia of bulbar conjunctiva of eyes, can be obviously improved. The medicine composition can be effectively used for treating xerophthalmia caused by video terminals, middle-aged and elderly xerophthalmia or diabetic xerophthalmia. Moreover, the clinical effect of the medicine composition is obviously superior to that of the Western medicine Tears Natural II group and the traditional Chinese medical science acupuncture group. The medicine composition is high in safety and good economic benefit, and a new medicine selection is provided for clinically treating the xerophthalmia.
Description
technical field [0001] The invention relates to a pharmaceutical composition for treating dry eye, its preparation method and application. Background technique [0002] With the development of society and the acceleration of the pace of life, dry eye has become a common, frequently-occurring, and refractory disease in ophthalmology. Dry eye syndrome has complicated etiology and complicated pathological process. It is a common ocular surface disease in ophthalmology. The patient's tear secretion is significantly reduced or the tear composition is abnormal, the tear film breakup time is shortened, the corneal epithelium is punctate, and the fluorescein staining is positive. Since the tear film can no longer assume its barrier, immunomodulatory, and mechanical detritus removal and antimicrobial roles, the sensory nerve-rich cornea is directly exposed to the outside world, plus viscous debris deposited in the conjunctival sac and filamentous corneal exfoliation Epithelial stimu...
Claims
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Application Information
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