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Chinese traditional medical composition for treating primary hepatic carcinoma and preparation method thereof

A technology for primary liver cancer and a composition, which is applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve problems such as the need to improve the efficacy of targeted therapy for liver cancer, the insensitivity of liver cancer, and the inability to operate.

Active Publication Date: 2012-12-05
LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current treatment for primary liver cancer is mainly early surgery. However, most patients with liver cancer are already in the middle and late stage when they are diagnosed, and they are no longer able to be operated on. The curative effect of the treatment also needs to be improved, which makes the method of traditional Chinese medicine treatment of this disease attract attention

Method used

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  • Chinese traditional medical composition for treating primary hepatic carcinoma and preparation method thereof
  • Chinese traditional medical composition for treating primary hepatic carcinoma and preparation method thereof
  • Chinese traditional medical composition for treating primary hepatic carcinoma and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1 ( Preparation of granules)

[0033] Weigh the following raw materials: 90 grams of Scutellaria barbata, 45 grams of snakeberry, 45 grams of Solanum nigrum, 90 grams of Sunburned turtle shell, 36 grams of Zhipinellia, 45 grams of cat's claw grass, 45 grams of turmeric, 45 grams of Polygonum cuspidatum, 45 grams of mistletoe, 36 grams of Atractylodes macrocephala, 45 grams of Poria cocos, 36 grams of bergamot, 45 grams of lacquer, and 36 grams of Ligustrum lucidum; grind the broiled turtle shell and poria cocos in the above raw materials into fine powder, and pass through a 80-mesh sieve; Extract volatile oil and water decoction from turmeric; crush knotweed and mistletoe into coarse powder, extract by percolation with 60-80% ethanol; concentrate the rest of the medicinal materials to 1-2g / ml after water extraction, add 95% ethanol, precipitate, take Supernatant liquid; the supernatant liquid is combined with the percolation method, and after recovering the et...

Embodiment 2

[0034] Example 2 ( Preparation of capsules)

[0035] Weigh the raw materials of the following weights: 120 grams of Scutellaria barbata, 45 grams of snakeberry, 45 grams of Solanum nigrum, 90 grams of broiled turtle shell, 30 grams of pinellia chinensis, 30 grams of cat's claw grass, 45 grams of turmeric, 45 grams of knotweed , 45 grams of mistletoe, 36 grams of Atractylodes macrocephala, 45 grams of Poria cocos, 27 grams of bergamot, 45 grams of lacquer, and 36 grams of Ligustrum lucidum; grind the sun-burned turtle shell and Poria cocos in the above raw materials into fine powder, and pass through a 80-mesh sieve; Extract volatile oil and water decoction with turmeric; crush knotweed and mistletoe into coarse powder, extract by percolation with 60-80% ethanol; concentrate the rest of the medicinal materials to 1-2g / ml after water extraction, add 95% ethanol, precipitate, Take the supernatant; combine the supernatant with the percolation method, recycle the ethanol and then...

Embodiment 3

[0036] Embodiment 3 ( preparation of tablets)

[0037] Weigh the following raw materials: Banzhilian 90 grams, Snakeberry 45 grams, Solanum nigrum 45 grams, Sunburned turtle shell 60 grams, Pinellia chinensis 30 grams, Cat’s Claw 30 grams, Curcuma 45 grams, Polygonum cuspidatum 45 grams , 45 grams of mistletoe, 36 grams of Atractylodes macrocephala, 45 grams of Poria cocos, 27 grams of bergamot, 27 grams of lacquer, and 45 grams of Ligustrum lucidum; grind the broiled turtle shell and Poria cocos in the above raw materials into fine powder, and pass through a 80-mesh sieve; Extract volatile oil and water decoction with turmeric; crush knotweed and mistletoe into coarse powder, extract by percolation with 60-80% ethanol; concentrate the rest of the medicinal materials to 1-2g / ml after water extraction, add 95% ethanol, precipitate, Take the supernatant; combine the supernatant with the percolation method, recover the ethanol and then combine with the water decoction of bergam...

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PUM

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Abstract

The invention discloses a Chinese traditional medical composition for treating primary hepatic carcinoma. The Chinese traditional medical composition comprises the effective components of sculellaria barbata, Indian strawberry, nightshade, roasted nightshade, prepared pinellia ternate, ternate buttercup root, radix curcumae, polygonum cuspidatum, mistletoe, rhizoma atractylodis macrocephalae, fingered citron, wartwort and fructus ligustri lucidi. The Chinese traditional medical composition provided by the invention can be particles, capsules, troches, pills or oral solutions and has the effects of inhibiting proliferation of hepatoma carcinoma cells and promoting aging, apoptosis and anoikis of the hepatoma carcinoma cells and can be used to treat the primary hepatic carcinoma. The invention further discloses a preparation method of the Chinese traditional medical composition.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating primary liver cancer and a preparation method thereof. Background technique [0002] Primary liver cancer is one of the common malignant tumors in my country. Its onset is insidious, its progression is rapid, its treatment effect is not good, and its prognosis is extremely poor. It is known as the "king of cancers". The current treatment for primary liver cancer is mainly early surgery. However, most patients with liver cancer are already in the middle and late stage when they are diagnosed, and they are no longer able to be operated on. The curative effect of the treatment also needs to be improved, so that the method of traditional Chinese medicine treatment of this disease is paid attention to. TCM treatment based on syndrome differentiation has been widely used in all aspects of comprehensive treatment such as liver cancer surgery, radiotherapy, interventional and rad...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P35/00A61K35/56A61K35/586
Inventor 胡兵安红梅沈克平
Owner LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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