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Composition with antialcoholism and hepatoprotective effect

A technology for detoxification and liver protection, composition, applied in the direction of drug combination, medical preparation containing active ingredients, application, etc., can solve the problem of inability to remove ethanol and its metabolite acetaldehyde, no obvious protective effect, human central nervous system damage and other problems, to achieve the effect of soothing people's mood after drinking, protecting the central nervous system, and reducing drowsiness

Inactive Publication Date: 2013-01-02
GUIZHOU INST OF BIOLOGY +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This kind of anti-alcoholic medicine is characterized by taking it before drinking to reduce the amount of alcohol entering the blood, and taking it after drinking can not remove ethanol and its metabolite acetaldehyde
The second category is hepatoprotective drugs, which mainly have a protective effect on the liver system, but have no obvious protective effect on other systems, such as the cardiovascular system.
The third type is the stimulant type. The drug enters the body to produce a corticosteroid stress effect, neutralizes the inhibitory effect of alcohol on the central nervous system, and achieves the purpose of sobering up. damage to the central nervous system

Method used

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  • Composition with antialcoholism and hepatoprotective effect
  • Composition with antialcoholism and hepatoprotective effect
  • Composition with antialcoholism and hepatoprotective effect

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] The preparation of embodiment 1 hangover vinegar

[0070] (1) Take 120kg of kudzu flower, 200kg of Hovenia dulcis, 15kg of dandelion, 15kg of black plum, and 50kg of licorice, add 6 times of water and heat for extraction for 2 hours, filter, add 5 times of water to extract the filter residue for 3 hours. Combine twice filtrate, adjust crude drug amount to be 100g / L;

[0071] (2) Add clarifying agent, let it stand for 12 hours, and filter;

[0072] (3) Add 2.5kg of alanine and 3.5kg of glutamine to the filtrate and stir evenly;

[0073] (4) Add rice vinegar and sucrose to the mixture in step (3) to obtain hangover vinegar.

[0074] Dosage: 50mL half an hour before each drink.

Embodiment 2

[0075] The preparation of embodiment 2 hangover vinegar

[0076] (1) Take 60kg of kudzu flower, 100kg of Hovenia dulcis, 30kg of dandelion, 10kg of black plum, and 20kg of licorice, add 10 times of water and heat for extraction for 1 hour, filter, add 2 times of water to extract the filter residue for 5 hours. Combine twice filtrate, adjust crude drug amount to be 200g / L;

[0077] (2) Add clarifying agent, let it stand for 10 hours, and filter;

[0078] (3) Add 3kg of alanine and 4kg of glutamine to the filtrate, and stir evenly;

[0079] (4) Add rice vinegar and sucrose to the mixture in step (3) to obtain hangover vinegar.

[0080] The preparation of embodiment 2 hangover capsules

[0081] (1) Get 100kg of kudzu flower, 100kg of Hovenia dulcis, 50kg of dandelion, 50kg of black plum, 50kg of licorice, add 10 times the amount of 80% ethanol to reflux and extract twice, filter, merge twice the filtrate, and concentrate to obtain extractum;

[0082] (2) Add 250kg dextrin to ...

Embodiment 3

[0085] The preparation of embodiment 3 hangover tablet

[0086] (1) Take 150kg of kudzu flower, 250kg of Hovenia dulcis, 150kg of dandelion, 40kg of black plum, and 80kg of licorice, add 5 times of water and heat to extract for 1 hour, and filter. Add 3 times of hydrothermal extraction to the filter residue for 0.5h, combine the two filtrates, concentrate to a relative density of 1.02-1.25, add 95% ethanol until the percentage of ethanol is 50%, and then let stand for more than 10h;

[0087] (2) Filter and concentrate the filtrate to a relative density of 1.35;

[0088] (3) Add 200kg of dextrin, 5kg of alanine, and 7kg of glutamine to make a soft material, sieve, and press into tablets. Dosage: Take two tablets half an hour before drinking alcohol.

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Abstract

The invention relates to a composition with antialcoholism and hepatoprotective effect. The composition comprises flowers of kudzuvine, hovenia acerba, dandelion, licorice, dark plum, alanine, and glutamine in proportion, and can be processed to prepare various products with antialcoholism and hepatoprotective effect. The composition has the effects of improving human tolerance to alcohol, preventing acute alcoholism, assisting treatment of alcoholic hepatic injury, alcohol allergy, and the like. In addition, the invention also relates to a method for preparing various food and medicaments by the composition.

Description

technical field [0001] The invention relates to a composition with anti-alcoholic and liver-protecting properties and its application in the preparation of anti-alcoholic and anti-alcoholic drug and food, belonging to the technical field of drugs and food. Background technique [0002] China is a big wine producing and consuming country. The annual consumption of alcoholic beverages reaches more than 20 million tons, and the number of people who are addicted to or dependent on alcohol reaches about 200 million. The rate of acute and chronic alcoholism is increasing day by day. Acute alcohol poisoning, commonly known as drunkenness, is the loss process of the central nervous system, digestive system, respiratory system, cardiovascular and cerebrovascular systems caused by drinking excessive alcohol or alcoholic beverages, manifested as emotional loss, disturbance of consciousness, respiratory depression, and even death Wait. The incidence of fatty liver, liver cirrhosis, and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/736A61P39/06A61P39/02A61P1/16A61P25/28A61P25/20A23L1/29A23L33/00
Inventor 贾强向兴泉罗文敏林泽武孙超付军龙汉武戚燕强向立容祁翔刘燕
Owner GUIZHOU INST OF BIOLOGY
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