Dual-module imaging system
A dual-mode imaging and laser technology, which is applied in the field of biomedical imaging, can solve the problem of sub-micron photoacoustic-fluorescence dual-mode imaging system without resolution, and achieve the effects of saving costs, reducing usage, and improving imaging accuracy
Active Publication Date: 2014-08-27
SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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To sum up, there is no photoacoustic-fluorescence dual-mode imaging system with sub-micron resolution in the prior art.
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[0009] The following describes in detail the embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein the same or similar reference numerals refer to the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary, only used to explain the present invention, and should not be construed as a limitation of the present invention.
[0010] In the description of the present invention, the orientation or positional relationship indicated by the terms "inner", "outer", "longitudinal", "lateral", "upper", "lower", "top", "bottom", etc. are based on the drawings The illustrated orientation or positional relationship is only for the convenience of describing the present invention, rather than requiring the present invention to be constructed and operated in a specific orientation, and therefore should not be construed as ...
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The invention discloses a dual-module imaging system, which comprises a laser generation device, a laser pre-processing device, a three-dimensional scanning device, an object lens, a miniature ultrasonic transducer, a water tank, a data acquisition card, a fluorescent signal separation device, a fluorescent signal processing device, a computer, a spectroscope and a first photoelectric detector, wherein the laser pre-processing device is used for pre-processing laser; the three-dimensional scanning device is used for controlling a laser light path; the object lens is used for focusing laser; the miniature ultrasonic transducer is used for transforming a photoacoustic signal into a first electrical signal; the object lens and the miniature ultrasonic transducer are arranged in the water tank; the data acquisition card is used for acquiring the first electrical signal; the fluorescent signal separation device is used for separating a fluorescent signal from reflection laser; the fluorescent signal processing device is used for transforming the fluorescent signal into a second electrical signal; and the computer is used for transforming the first electrical signal and the second electrical signal into a photo-acoustic image and a fluorescent image. By the dual-module imaging system, the precision of photoacoustic-fluorescent dual modules can be improved to a submicron level.
Description
technical field [0001] The invention relates to biomedical imaging technology, in particular to a dual-mode imaging system. Background technique [0002] The photoacoustic imaging technology in the field of biomedical imaging uses the optical absorption characteristics of biological tissues as a contrast mechanism to obtain the chemical composition and physiological functional characteristics of the organism. Confocal fluorescence imaging technology provides specific imaging of the distribution, structure and function of biological tissue molecules by means of fluorescent molecular targeting. Since both photoacoustic imaging technology and fluorescence confocal imaging technology have high resolution and are in an order of magnitude, more biological tissue information can be obtained by combining photoacoustic imaging technology and fluorescence confocal imaging technology. , so as to further improve the efficiency of medical diagnosis and treatment. In addition, achieving...
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IPC IPC(8): G01N21/17G01N21/64
Inventor 宋亮林日强郑炜白晓淞
Owner SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI