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Aqueous solution for preserving tissues and organs

An aqueous solution and organ technology, applied in the field of aqueous solutions, can solve problems such as the inability to guarantee the preservation of organs

Inactive Publication Date: 2013-03-06
GROUPE IGL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] As mentioned earlier, the main disadvantage of these solutions is that preservation of all organs is not guaranteed

Method used

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  • Aqueous solution for preserving tissues and organs
  • Aqueous solution for preserving tissues and organs
  • Aqueous solution for preserving tissues and organs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] Preparation of multi-organ aqueous preservation solution of the present invention

[0061] An aqueous storage solution was prepared, the composition of which is reproduced in Table 2 below:

[0062] Table 2

[0063]

[0064] The preparation of the solution consisted essentially of dissolving all the components in an aqueous solution and adjusting the pH of the obtained solution to 7.4 by adding NaOH.

Embodiment 2

[0066] In this example the performance on the kidneys and liver of the aqueous preservation solution according to the invention is compared with the BELZER-VIASPAN solution sold by DUPONT.

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PUM

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Abstract

The invention provides aqueous solution for preserving tissues and organs. The aqueous solution is extracellular, purified polyethylene glycol 35000 in molecular weight. Compared with preservation fluid currently on sale, the aqueous solution improves biochemical parameter and characteristics of functional parameters of perfused organs.

Description

technical field [0001] The present invention relates to an aqueous solution for preserving tissues and organs. The expression "tissue" refers in particular to veins, arteries, valves, blood vessels, etc., but is not limited thereto. The expression "solution for preserving organs" means an aqueous solution for preservation only, which can preserve various organs, especially but not limited to liver and kidney. Background technique [0002] After organs and tissues are removed from a donor, they undergo an unavoidable period of ischemia before they are transplanted into a recipient. Therefore, the fluid used to preserve organs must simultaneously meet 3 goals, namely: [0003] Rinse the graft so that it is free of residual blood, [0004] ●cools the organs, [0005] ● Ensure effective prevention and protection against damage caused by ischemia. [0006] The most common method used to preserve organs is static cryopreservation. The method consists in rinsing the removed o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N1/02
Inventor 乔治斯-安托万・洛佩斯西尔维娜・拉梅利亚维里厄
Owner GROUPE IGL
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