Sarafloxacin hydrochloride bactericide for silkworms and preparation method for capsules thereof

Abstract

The invention discloses a sarafloxacin hydrochloride bactericide for silkworms and a preparation method for capsules thereof. The bactericide consists of sarafloxacin hydrochloride, sucrose powder and sodium carbonate in a weight ratio of 1: (0.5-1.5): (1.5-2.5). The method comprises the following steps of: mixing the materials uniformly, preparing a soft material by using 50 to 90 weight percent ethanol solution as mucilage, granulating, drying, reshaping, mixing uniformly, filling into No.0 capsules, making plates by using aluminum plastic, and packing, wherein each capsule contains 0.1 gram of sarafloxacin hydrochloride. The results show that the water solubility, the quality stability and the controllability of the researched sarafloxacin hydrochloride capsules for the silkworms are obviously enhanced, and the capsules have an obvious prevention and control effect on bacterial silkworm septicemia caused by infection of bacillus such as bacillus thuringiensis or chromobacterium prodigiosum.

Description

technical field [0001] The invention relates to a preparation method of a fungicide and a capsule thereof. For example, as a broad-spectrum antibacterial agent and the preparation method of its capsules, especially a silkworm hydrochloric acid with a trade name of "Yadi Canfeng" for preventing and treating bacterial septicemia of silkworms caused by bacillus and bleeding bacteria A sarafloxacin fungicide and a preparation method of capsules thereof. Background technique [0002] Bombyx mori bacterial septicemia refers to bacteria invading the body fluids of silkworm bodies, silkworm chrysalis and silkworm moths, multiplying in large numbers and distributing to the whole body with the circulation of body fluids, causing severe systemic symptoms. The disease is divided into two types: primary and secondary . Bombyx mori bacterial septicemia occurs from time to time in sericulture production, especially in summer and autumn when the high temperature and humidity seasons are m...

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Problems solved by technology

[0006] The technical problem to be solved: In view of the existence of antibacterial agents for silkworms or the antibacterial spectrum is not wide enough, it is only effective for silkworm bacterial septicemia caused by bacillus, but the control effect on silkworm bacterial septicemia caused by bleeding bacteria is poor. Or the stability of the drug effect of the finished product is not good, which affects the use effect, or the raw material drug is a shared raw material drug for humans and animals, and the mixed use between humans and silkworms, livestock, and poultry leads to bacterial resistance and affects the human effect. Provide A preparation method of sarafloxacin hydrochloride bactericide for silkworms and its capsules; we use sarafloxacin hydrochloride as the main raw material, add a certain proportion of diluted co-solvent sucrose and sodium carbonate to the prescription, and prepare sarafloxacin hydrochloride capsules for silkworms The development of the production technology and the control test of silkworm bacterial septicemia

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