Sarafloxacin hydrochloride bactericide for silkworms and preparation method for capsules thereof

The technology of salafloxacin hydrochloride and salafloxacin acid is applied in the field of preparation of bactericides and capsules thereof, and can solve the problems of bacterial resistance, poor stability of finished products, and effects on human use.

Inactive Publication Date: 2013-04-03
JIANGSU UNIV OF SCI & TECH
View PDF3 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The technical problem to be solved: In view of the existence of antibacterial agents for silkworms or the antibacterial spectrum is not wide enough, it is only effective for silkworm bacterial septicemia caused by bacillus, but the control effect on silkworm bacterial septicemia caused by bleeding bacteria is poor. Or the stability of the drug effect of the finished product is not good, which affects the use effect, or the raw material drug is a shared raw material drug for humans and animals, and the mixed use betwe

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Sarafloxacin hydrochloride bactericide for silkworms and preparation method for capsules thereof
  • Sarafloxacin hydrochloride bactericide for silkworms and preparation method for capsules thereof
  • Sarafloxacin hydrochloride bactericide for silkworms and preparation method for capsules thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Example 1: Serafloxacin hydrochloride capsules for preventing and treating silkworm bacterial septicemia and its preparation method

[0057] Using the silkworm sarafloxacin hydrochloride capsule and its preparation method for preventing and treating silkworm bacterial septicemia of the present invention, the proportion of each component in the silkworm sarafloxacin hydrochloride capsule prescription is: the original powder of sarafloxacin hydrochloride and the dilution cosolvent The weight ratio of sucrose powder and sodium carbonate is 1:0.5:2.5; that is, each capsule contains 0.1 g of sarafloxacin hydrochloride, 0.05 g of sucrose powder and 0.25 g of sodium carbonate. Its preparation method, that is, the production process, is as follows: Weigh the raw and auxiliary materials according to the dosage of the prescription, mix them uniformly, use 90% ethanol solution as a binder to make a soft material, dry, granulate, and mix evenly, and pass the intermediate inspection ...

Embodiment 2

[0058] Example 2: Serafloxacin hydrochloride capsules for silkworms used for preventing and treating bacterial septicemia in silkworms and its preparation method

[0059] Using the silkworm sarafloxacin hydrochloride capsule and its preparation method for preventing and treating silkworm bacterial septicemia of the present invention, the proportion of each component in the silkworm sarafloxacin hydrochloride capsule prescription is: the original powder of sarafloxacin hydrochloride and the dilution cosolvent The weight ratio of sucrose powder and sodium carbonate is 1:1:2; that is, each capsule contains 0.1 g of sarafloxacin hydrochloride, 0.1 g of sucrose powder and 0.2 g of sodium carbonate. Its preparation method, that is, the production process, is as follows: Weigh the raw and auxiliary materials according to the dosage of the prescription, mix them uniformly, use 75% ethanol solution as a binder to make a soft material, dry, granulate, and mix evenly, and pass the interme...

Embodiment 3

[0060] Example 3: Serafloxacin hydrochloride capsules for preventing and treating bacterial septicemia in silkworms and its preparation method

[0061]Using the silkworm sarafloxacin hydrochloride capsule and its preparation method for preventing and treating silkworm bacterial septicemia of the present invention, the proportion of each component in the silkworm sarafloxacin hydrochloride capsule prescription is: the original powder of sarafloxacin hydrochloride and the dilution cosolvent The weight ratio of sucrose powder and sodium carbonate is 1:1.5:1.5; that is, each capsule contains 0.1 g of sarafloxacin hydrochloride, 0.15 g of sucrose powder and 0.15 g of sodium carbonate. Its preparation method, that is, the production process, is as follows: Weigh the raw and auxiliary materials according to the dosage of the prescription, mix them uniformly, use 60% ethanol solution as a binder to make a soft material, dry, granulate, and mix evenly, and pass the intermediate inspecti...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a sarafloxacin hydrochloride bactericide for silkworms and a preparation method for capsules thereof. The bactericide consists of sarafloxacin hydrochloride, sucrose powder and sodium carbonate in a weight ratio of 1: (0.5-1.5): (1.5-2.5). The method comprises the following steps of: mixing the materials uniformly, preparing a soft material by using 50 to 90 weight percent ethanol solution as mucilage, granulating, drying, reshaping, mixing uniformly, filling into No.0 capsules, making plates by using aluminum plastic, and packing, wherein each capsule contains 0.1 gram of sarafloxacin hydrochloride. The results show that the water solubility, the quality stability and the controllability of the researched sarafloxacin hydrochloride capsules for the silkworms are obviously enhanced, and the capsules have an obvious prevention and control effect on bacterial silkworm septicemia caused by infection of bacillus such as bacillus thuringiensis or chromobacterium prodigiosum.

Description

technical field [0001] The invention relates to a preparation method of a fungicide and a capsule thereof. For example, as a broad-spectrum antibacterial agent and the preparation method of its capsules, especially a silkworm hydrochloric acid with a trade name of "Yadi Canfeng" for preventing and treating bacterial septicemia of silkworms caused by bacillus and bleeding bacteria A sarafloxacin fungicide and a preparation method of capsules thereof. Background technique [0002] Bombyx mori bacterial septicemia refers to bacteria invading the body fluids of silkworm bodies, silkworm chrysalis and silkworm moths, multiplying in large numbers and distributing to the whole body with the circulation of body fluids, causing severe systemic symptoms. The disease is divided into two types: primary and secondary . Bombyx mori bacterial septicemia occurs from time to time in sericulture production, especially in summer and autumn when the high temperature and humidity seasons are m...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K31/496A61K9/48A61P31/04
Inventor 王玉华康国平钟馗黄可威赫荣帆徐勤文王娟陈俊骥王长春
Owner JIANGSU UNIV OF SCI & TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap