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Pharmaceutical composition for treating malignant tumors and preparation method thereof

A malignant tumor and composition technology, which is applied in the direction of drug combination, antineoplastic drugs, and pharmaceutical formulations, can solve the problems of different drugs and different drug effects, and achieve the effects of prolonging survival, easy promotion, and simple preparation process

Active Publication Date: 2013-04-17
NANTONG HONGCI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, there have been many reports on the treatment of cancer with traditional Chinese medicines, but the principles of using traditional Chinese medicines to treat cancer are different, and the effects of the medicines are also different. There should be ample room for exploration

Method used

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  • Pharmaceutical composition for treating malignant tumors and preparation method thereof
  • Pharmaceutical composition for treating malignant tumors and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Formulation Example 1: The preparation of granules of the present invention

[0062] Prescription: Poria 4000g, Arctium 1500g, Hedyotis diffusa 400g, Banzhilian 600g, Achyranthes bidentata 1200g, atorvastatin calcium 0.4g.

[0063] Preparation Process:

[0064] 1) Weigh Hedyotis diffusa, Scutellaria barbata, Poria cocos, Arctium, Achyranthes bidentata according to the above prescription, dry and crush them through an 80-mesh sieve, add 8 times the amount of ethanol to reflux and extract twice, each time for 4 hours, combine the extracts, filter After that, the ethanol was recovered under reduced pressure and concentrated to a thick paste, and dried in vacuo to obtain the ethanol extract;

[0065] 2) Take the dregs after alcohol extraction in step 1, add 8 times the amount of water to decoct twice, 4 hours each time, combine the decoction, concentrate the filtrate under reduced pressure to a relative density of 1.15-1.20, and vacuum dry to obtain the water extract;

...

Embodiment 2

[0067] Preparation Example 2: The preparation of granules of the present invention

[0068] Prescription: Poria 5000g, Arctium 1500g, Hedyotis diffusa 300g, Banzhilian 400g, Achyranthes bidentata 1800g, atorvastatin calcium 0.6g.

[0069] Preparation Process:

[0070] 1) Weigh Hedyotis diffusa, Scutellaria barbata, Poria cocos, Burdock fruit, and Achyranthes bidentata according to the above prescription, dry and crush them through an 80-mesh sieve, add 10 times the amount of ethanol to reflux and extract twice, each time for 2 hours, combine the extracts, filter After that, the ethanol was recovered under reduced pressure and concentrated to a thick paste, and dried in vacuo to obtain the ethanol extract;

[0071] 2) Take the medicinal residue after alcohol extraction, add 10 times the amount of water to decoct twice, 2 hours each time, combine the decoction, concentrate the filtrate under reduced pressure to a relative density of 1.15-1.20, and vacuum dry to obtain the wat...

Embodiment 3

[0073] Preparation Example 3: The preparation of granule of the present invention

[0074] Prescription: Poria 6000g, Arctium 1800g, Hedyotis diffusa 800g, Banzhilian 1000g, Achyranthes bidentata 2000g, atorvastatin calcium 1g.

[0075] Preparation Process:

[0076] 1) Weigh Hedyotis diffusa, Scutellaria barbata, Poria cocos, Arctium, Achyranthes bidentata according to the above prescription, dry and crush them through an 80-mesh sieve, add 8 times the amount of ethanol to reflux and extract 3 times, each time for 2 hours, combine the extracts, filter After that, the ethanol was recovered under reduced pressure and concentrated to a thick paste, and dried in vacuo to obtain the ethanol extract;

[0077] 2) Take the dregs after alcohol extraction in step 1, add 8 times the amount of water to decoct 3 times, 2 hours each time, combine the decoction, concentrate the filtrate under reduced pressure to a relative density of 1.15-1.20, and vacuum dry to obtain the water extract; ...

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Abstract

The invention discloses a medicament for treating malignant tumors, and relates to the technical field of traditional Chinese medicines. The medicament is prepared by processing oldenlandia diffusa, sculellaria barbata, poria cocos, fructus arctii, achyranthes and atorvastatin calcium as raw materials according to the requirements of compatibility, and the medicament is preferably prepared into capsules and tablets. The pharmaceutical composition has certain symptom relieving, tumor shrinkage and tumor growth inhibition effects and the like on various malignant tumors such as lung cancers, liver cancers, gastric cancers, colorectal cancers, breast cancers, brain tumors and lymph cancers, can enhance the human immunity and prolong the lives of patients with tumors, and can effectively relieve adverse reactions such as leukopenia, dizziness, tireness, power leakage, emaciation, poor stomach intake and nausea and vomiting caused by the radiotherapy and chemotherapy of tumors.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating malignant tumors. Background technique [0002] According to the statistics of the World Health Organization (WHO), the average number of deaths from malignant tumors in the world is 6.9 million every year, and 8.7 million new cases are diagnosed, and this number is still increasing year by year. There are 10 million newly diagnosed tumor patients in the world every year, and it is estimated that by 2020, 20 million new tumors will occur worldwide every year. According to the statistics of the Ministry of Health of my country, there are about 1.06 million new patients with malignant tumors and about 1.067 million patients with benign tumors in my country every year. Every year, about 1.54 million people die from cancer in my country, and cancer (tumor) has become the second largest disease in my country after cardiov...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/748A61P35/00A61K31/40
Inventor 柳元苏传付
Owner NANTONG HONGCI PHARMA
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