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Improved registration method for image with obvious local deformation

A local deformation and obvious technology, applied in image analysis, image data processing, instruments, etc., can solve problems such as over-constraint, registration accuracy drop, and over-smoothing

Inactive Publication Date: 2015-06-10
SOUTHERN MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Therefore, using the FFD model as the deformation model, L 2 When the norm is used as a constraint item to construct the objective function, for images with severe local deformation and large and severe displacement fields, problems of over-constraint and over-smoothing will occur, which will lead to a decrease in registration accuracy

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  • Improved registration method for image with obvious local deformation
  • Improved registration method for image with obvious local deformation
  • Improved registration method for image with obvious local deformation

Examples

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example 1

[0029] In this embodiment, two simulated human brain MR images in BrainWeb are taken as an example to describe the registration method of the present invention.

[0030] see figure 1 , the specific implementation steps of the registration method of the improved local deformation obvious image of the present invention are as follows:

[0031] Step 1, read in respectively image 3 (a) and image 3 (b), and will image 3 (a) As a reference image I, image 3 (b) as a floating image J. In order to improve the accuracy of calculation and speed up the convergence of the program, the read-in image 3 (a) and image 3(b) Convert from unsigned integer type to double-precision floating-point type, and then linearly transform their gray values ​​into 0~1.

[0032] Step 2, to Indicates the position of the control point, n x ×n y ×n z Indicates the grid size, using the B-spline multi-resolution grid free deformation model shown in the following formula (II) to the floating imag...

example 2

[0050] In this example, liver images obtained by CT scanning in the arterial phase and venous phase after contrast agent injection Figure 5 (a) and Figure 5 (b) Take the registration method as an example, the specific steps are as follows.

[0051] first read in Figure 5 (a) and Figure 5 (b), and will Figure 5 (a) as a reference image, Figure 5 (b) as a floating image, and then follow the steps described in Example 1 for registration. In this example, the sizes of the three-layer deformed grids are 32×32×32, 16×16×16, and 8×8×8 in sequence; λ in formula (I) is 0.05, and γ is 0.001. Registration results such as Figure 6 (a) Column shown above.

[0052] In order to verify the effect of the method of the present invention, this example still refers to the prior art described in example 1 to Figure 5 (a) The reference image shown and Figure 5 The floating images shown in (b) are registered, and the registration results are as follows Figure 6 (b) Column shown a...

example 3

[0054] Example 3 (Research on the influence of λ value on registration effect)

[0055] In order to verify that the method proposed by the inventor has higher registration accuracy than the traditional free deformation registration method, and is more robust to the weight parameter λ, in this example, λ is set to 0.001, 0.005, 0.01, 0.05 respectively , 0.1 these 5 different values, carry out 5 groups of experimental comparisons.

[0056] In this example, use image 3 (a) as a reference image, image 3 (b) As a floating image, use the improved registration method for images with obvious local deformation and the existing method described in Example 1 for registration respectively. The comparison results are shown in Figure 7 . in Figure 7 (a) is listed as the residual map obtained by using the improved registration method of locally deformed images, Figure 7 (b) is listed as the residual map obtained by registration using the existing method described in Example 1. Fro...

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Abstract

The invention relates to an improved registration method for an image with obvious local deformation. The method comprises the following steps of: inputting a reference image I and a floating image J to be registered respectively; and registering by using a multi-resolution grid free deformation method of B spline, wherein in the multi-resolution grid free deformation method of the B spline, a registration process of the floating image T (J) and the reference image I after each layer of deformation comprises the steps of: correspondingly substituting components in a formula (1) with absolute values of being greater than gamma, keeping the rest unchanged, and finally iteratively solving by using a 1-BFGS (Broyden-Fletcher-Goldfarb-Shanno) method by taking the newly obtained function as a target function, and finishing registration of the floating image T (J) and the reference image I after the layer of deformation when two adjacent iterations meet the preset end conditions. According to the registration method, the accuracy and the robustness of the registration can be obviously improved.

Description

technical field [0001] The invention relates to general image data processing, in particular to a graphic image conversion method in an image plane, which is suitable for image registration with relatively obvious local deformation. Background technique [0002] So far, for the image registration problem with obvious local deformation, the traditional free deformation (FFD) registration method is the most commonly used. The objective function of this method is divided into two items, the similarity measure and the constraint item. Among them, the deformation is based on The FFD model of B-spline, the constraint item is the two-norm model L 2 (ie the Euclidean norm). This traditional FFD method is often used in image registration, target tracking, motion analysis, etc., and has a good effect on simulating the local deformation of the target. For example, D.Ruecker used this method in mammary gland registration, and E.Bardinet used this method in left ventricular motion anal...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T7/00
Inventor 卢振泰胡昊冯前进陈武凡
Owner SOUTHERN MEDICAL UNIVERSITY