A device and a method for using a multi-focusing camera to realize collection of multi-resolution images are disclosed, comprising five focusing cameras having restraining relationship with others, wherein four of them are located at the same horizontal plane and on four top points of the same square, and the four cameras have the identical focus which is set as f; the rest 1 camera is located in the direction of the four cameras, axes line of the camera is perpendicular to the surfaces of four cameras and passes a central point O of the square, and the distance from the fifth camera to the rest four cameras is d, the focus of the camera is set as f, and initial setting is performed to the parameters and locations of the five focusing cameras with the location relationship satisfying the following restraint: f=f+d. The invention achieves the function of lossless zooming film of the multi-focusing camera with adjustable details of scenes and images, and with flexible and controllable structure, the invention can rapidly collect the multi-resolution images in the large visual scene.