Fiber porous titanium microsphere with drug loading capability
A porous titanium and fiber technology, applied in the field of materials in the field of biomedical engineering technology, can solve problems such as single function
Inactive Publication Date: 2013-05-08
SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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[0003] However, the material described in the above-mentioned patent is limited by its material characteristics and can only be used for the repair of human bone defects, and its function is relatively single. Therefore, a material that not only has the characteristics of a fibrous porous material but also can be loaded with drugs according to different orthopedic treatment purposes , has always been one of the research directions for those skilled in the art
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[0011] see figure 1 , the drug-loaded fibrous porous titanium microspheres of the present invention include a fibrous porous titanium microsphere body 1 and a drug-loaded coating 2 wrapped on the outer surface of the fibrous porous titanium microsphere body 1, the drug-loaded coating 2 is hydroxyl Apatite layer, the fibrous porous titanium microsphere body 1 is made of pure titanium fibers.
[0012] The hydroxyapatite (HA) used in the drug-loaded coating 2 can promote bone ingrowth, and at the same time, depending on the purpose of treatment, it can be loaded with anti-osteoporosis drugs and chemotherapy drugs for bone tumors.
[0013] The above embodiments are only for the purpose of illustrating the present invention, rather than limiting the present invention. Those skilled in the relevant technical fields can also make various changes or modifications without departing from the spirit and scope of the present invention. Therefore, all equivalent The technical solutions sh...
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The invention relates to a fiber porous titanium microsphere with drug loading capability, which comprises a fiber porous titanium microsphere body, and also comprises a drug loaded coating coated on the outer surface of the fiber porous titanium microsphere body. According to the fiber porous titanium microsphere with drug loading capability of the invention, a drug loaded coating is coated on the surface of the fiber porous titanium microsphere, which can not only promote bone ingrowth, but also has a drug loading function. According to different treatment purposes, corresponding drugs can be added on the drug loaded coating of the fiber porous titanium microsphere so as to widen the application functions of the fiber porous titanium microsphere.
Description
technical field [0001] The invention relates to a material in the technical field of biomedical engineering, in particular to a drug-loadable fibrous porous titanium microsphere. Background technique [0002] The patent with the publication number CN101584880 provides a material for repairing human bone defects. The material includes: porous porous titanium microspheres and a nano-strontium apatite layer wrapped outside the microspheres. The porous titanium microspheres are composed of Made of pure titanium fibers, porous titanium microspheres and nano-strontium apatite composite repair bone defects, which can promote the adhesion, proliferation and differentiation of osteoblasts while maintaining the characteristics of the original porous materials; more effectively induce Bone formation, enhanced osseointegration and osseobonding. [0003] However, the material described in the above-mentioned patent is limited by its material characteristics and can only be used for the ...
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Login to View More IPC IPC(8): A61L27/56A61L27/54A61L27/20A61K9/14A61K47/36
Inventor 郝永强何国戴尅戎
Owner SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE