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Compositions of nutrition supplementation for nutritional deficiencies and method of use therefore

A technology for nutritional supplements and carbohydrates, which can be used in drug combinations, active ingredients of iodine compounds, active ingredients of heterocyclic compounds, etc., and can solve the problem of not being recommended.

Active Publication Date: 2013-05-08
全球营养公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, hydroxyurea has some adverse side effects, such as myelosuppression, and lifelong dosing may not be recommended

Method used

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  • Compositions of nutrition supplementation for nutritional deficiencies and method of use therefore
  • Compositions of nutrition supplementation for nutritional deficiencies and method of use therefore
  • Compositions of nutrition supplementation for nutritional deficiencies and method of use therefore

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] Example 1: Nutritional Supplement Research

[0077] Twelve children (SS) with sickle cell anemia (SCA) aged 6-12 years were randomized to placebo (5) and supplement (7) and given placebo biscuits (for placebo ) or supplement cookies (for the supplement group). Normal children without SCA but of similar age served as controls (AA, n=9). Information was collected on anthropometric measurements, body composition, resting energy expenditure, blood amino acid levels and reactive oxygen species production, and levels of natural antioxidant consumption. Data analyzes were performed on an intention-to-treat (gold standard) basis, meaning that all participants were included in the analysis for their assigned group regardless of how long each participant had been in the study. The number of participants (n) during the study was as follows:

[0078] Baseline; AA: n=9, placebo: n=5, supplemented SCA group: n=7

[0079] SCA Intervention Period

[0080] 2 weeks: placebo n=5,...

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PUM

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Abstract

A nutritional supplement composition for treating nutritional deficiencies caused by a medical condition in subjects is disclosed. The present application further discloses a method of using a nutritional supplements composition for treating a subject with complications resulting from sickle cell anemia. The method comprises administering to a subject an effective amount of the nutritional supplement.

Description

[0001] This application claims priority to US Application Serial No. 13 / 105,383, filed May 11, 2011, and Provisional Application No. 61 / 348,430, filed May 26, 2010. All of the aforementioned applications are hereby incorporated by reference in their entirety. field of invention [0002] The present application relates generally to the field of nutritional supplements designed for the treatment of nutritional problems resulting from a medical condition of an individual. In particular, the application relates to the prevention and treatment of nutritional deficiencies in individuals with sickle cell anemia. Background of the invention [0003] Sickle cell disease is an inherited hematological disorder based on mutations in the hemoglobin beta-globin gene. The mutated hemoglobin aggregates when deoxygenated and causes red blood cells to change shape (sickle). This alteration of red blood cells leads to occlusion of blood vessels leading to complications such as stroke, pulmon...

Claims

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Application Information

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IPC IPC(8): A23L1/29A61P3/02A61P3/00A23L1/305A23L1/30A23L33/00A23L33/15A23L33/155A61K33/24
CPCA23L1/302A23L1/3051A23L1/293A23L1/304A23L1/3002A23L33/30A23L33/105A23L33/115A23L33/15A23L33/155A23L33/16A23L33/17A23L33/175A61K31/015A61K31/07A61K31/198A61K31/355A61K31/375A61K31/4172A61K31/455A61K31/51A61K31/525A61K31/59A61K31/675A61K31/714A61K31/7004A61P3/00A61P3/02A61P31/18A61P35/00A61P7/06A61K33/24A23V2002/00A61K33/00A61K33/06A61K33/18A61K33/26A61K33/30A61K33/32A61K36/88
Inventor 杰奎琳·M·赫伯特乔纳森·K·斯泰勒斯卡耶林·厄米库尼海森斯·I·亚森斯
Owner 全球营养公司
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