Traditional Chinese medicine composition and preparation method thereof

A technology of composition and natural medicine, applied in the direction of drug combination, pharmaceutical formulation, anti-tumor drug, etc., can solve the problems of dehydration, acid-base balance disorder, malnutrition, etc. in patients, and achieves enhanced inhibitory effect, increased inhibitory effect, and good synergy effect of action

Inactive Publication Date: 2013-07-03
张宗升
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AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Traditional Chinese medicine composition and preparation method thereof
  • Traditional Chinese medicine composition and preparation method thereof

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Experimental program
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Effect test

Embodiment approach

[0034] The first step: preparation of various extracts

[0035] (1) Preparation of the concentrated extract of Chinese yam longan longan decocted in water

[0036] According to the compatibility ratio of 1:1 or other ratios of 1-6:1, take yam and longan, soak in 10 times the amount of distilled water, soak for 1 hour, heat and decoct on an electric stove with asbestos net for 1 hour, filter with silk cloth, save the filtrate and medicinal residue Add 6 times more distilled water, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate to a small volume, filter with an ultrafiltration membrane, and dry under reduced pressure at 70°C for 36 hours in a vacuum drying oven to obtain a brown-yellow powder.

[0037] (2) Preparation of yam polysaccharide

[0038]Take dried yam powder, reflux extraction with 95% ethanol at 70°C for 3 times, each time for 4h, remove the supernatant, collect the filter residue, extract the filter residue with distilled wate...

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Abstract

The invention relates to a natural medicine composition, a preparation method thereof, and an application of the composition in preparation of a toxicity reducing and efficacy enhancing medicine for cancer chemotherapy. The natural medicine composition is composed of a Chinese yam and fructus piperis longi extract after water decoction and concentration, Chinese yam polysaccharide, a fructus piperis longi ethanol extract and piperine in a ratio of (2-6): (3-6): (3-4): (5-9). The composition has an excellent curative effect on diarrhea related with the cancer chemotherapy, and can enhance the effect on the cancer chemotherapy simultaneously.

Description

technical field [0001] The present invention relates to a kind of natural medicine composition, more specifically relate to a kind of natural medicine composition that is made up of Chinese yam Piper longum water decoction concentrated extract, Chinese yam polysaccharide, Piper longum ethanol extract and piperine, the natural medicine composition The preparation method and the application of the natural medicine composition in the preparation of medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs, whether used alone or in combination, can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P35/00A61P1/12A61K31/715A61K31/4525
Inventor 张宗升
Owner 张宗升
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