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Traditional Chinese medicine composition for treating polycystic kidney disease, and preparation method thereof

A technique for polycystic kidney disease and its composition, which is applied in the field of traditional Chinese medicine, can solve the problems of no unified method of syndrome differentiation and classification in traditional Chinese medicine, and few reports on the curative effect of traditional Chinese medicine compound prescriptions, so as to delay the deterioration of renal function, have no toxic side effects, and take less dosage Effect

Active Publication Date: 2013-07-03
SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no unified TCM syndrome differentiation method and standard for this disease at present, and clinicians mostly use their own experience to differentiate syndromes and types
In terms of traditional Chinese medicines for effective treatment, although the curative effects of several single medicines have been verified by experiments, there are still few reports on the specific curative effects of Chinese herbal medicines.

Method used

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  • Traditional Chinese medicine composition for treating polycystic kidney disease, and preparation method thereof
  • Traditional Chinese medicine composition for treating polycystic kidney disease, and preparation method thereof
  • Traditional Chinese medicine composition for treating polycystic kidney disease, and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0031] Weigh raw materials: Codonopsis 15 grams, Radix Astragali 15 grams, Angelica 10 grams, Radix Paeoniae Rubra 10 grams, Radix Paeoniae Alba 10 grams, Trigonum 10 grams, Cat’s Claw 10 grams, Pangolin powder 1 gram, Plantago 15 grams, 10 grams of mustard seed, 10 grams of Liuxingzi, 10 grams of drynaria, 10 grams of snakeberry, and 10 grams of Hedyotis.

[0032] Take half of the above raw materials (except pangolin powder), add 3 times the amount of water, soak for half an hour, decoct for 45 minutes, add 3 times the amount of water, decoct for 30 minutes, filter and combine the decoction liquid, add 0.5 g of pangolin powder, reduce Concentrate under reduced pressure, dry under reduced pressure to obtain dry extract, and pulverize into fine powder (over 80 mesh). The other half of the crude drug was crushed to 80 meshes, sterilized with CO60 (irradiation dose 8k), mixed with extract powder, added 0.5 g of pangolin powder, and added the following pharmaceutical excipients: m...

Embodiment 2

[0034]Weigh raw materials: Codonopsis 30 grams, Radix Astragali 30 grams, Angelica 15 grams, Radix Paeoniae Rubra 15 grams, Radix Paeoniae Alba 15 grams, Trigonum 15 grams, Cat’s Claw 30 grams, Pangolin powder 2 grams, Plantago 15 grams, 15 grams of mustard seed, 15 grams of Liuxingzi, 15 grams of drynaria, 15 grams of snakeberry, and 15 grams of Hedyotis.

[0035] Take half of the amount of raw materials in the above formula (except pangolin powder), add 8 times the amount of water, soak for half an hour, decoct for 30 minutes, add 8 times the amount of water, decoct for 45 minutes, filter and combine the decoction liquid, add pangolin powder 1 grams, concentrated under reduced pressure, dried under reduced pressure to obtain a dry extract, and crushed into fine powder (over 80 mesh). The other half of the crude drug was crushed to 80 meshes, sterilized with CO60 (irradiation dose 8k), mixed with extract powder, added 1 g of pangolin powder, and added the following pharmaceut...

Embodiment 3

[0037] Weigh raw materials: Codonopsis 18 grams, Radix Astragali 18 grams, Angelica 12 grams, Radix Paeoniae Rubra 12 grams, Radix Paeoniae Alba 12 grams, Trigonum 12 grams, Cat’s Claw 20 grams, Pangolin powder 1.6 grams, Plantago 12 grams, 12 grams of mustard seed, 12 grams of Liuxingzi, 12 grams of drynaria, 12 grams of snakeberry, and 12 grams of Hedyotis.

[0038] Take half of the amount of raw materials (except pangolin powder) in the above formula, add 5 times the amount of water, soak for half an hour, decoct for 40 minutes, add 5 times the amount of water, decoct for 40 minutes, filter and combine the decoction liquid, add 0.8 of pangolin powder grams, concentrated under reduced pressure, dried under reduced pressure to obtain a dry extract, and crushed into fine powder (over 80 mesh). The other half of the crude drug was crushed to 80 meshes, sterilized with CO60 (irradiation dose 8k), mixed with extract powder, added 0.8 g of pangolin powder, and added the following ...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating a polycystic kidney disease, which is mainly prepared by the following raw material medicine in parts by weight: 15-30 parts of pilose asiabell root, 15-30 parts of astragalus root, 10-15 parts of Chinese angelica root, 10-15 parts of red peony root, 10-15 parts of white peony root, 10-15 parts of burreed rhizome, 10-30 parts of ternate buttercup root, 1-2 parts of pangolin scales powder, 10-15 parts of plantain seed, 10-15 parts of white mustard seed, 10-15 parts of semenvaccariae, 10-15 parts of rhizome of drynaria, 10-15 parts of duchesnea indica and 10-15 parts of hedyotidis herba. Besides, the invention also discloses a method for preparing the traditional Chinese medicine composition. The traditional Chinese medicine composition has the function of improving the kidney function, renal tubules and glomeruli of a polycystic kidney disease patient, can effectively improve the clinical symptoms of patients such as waist and knee weakness, lower back swelling pain or sharp pain, physical and mental fatigue, intolerance to cold and cold limbs and limb numbness, can better treat the polycystic kidney disease, is convenient to take, and small in dosage, has no toxic side effect and is praised by patients.

Description

Technical field: [0001] The invention belongs to the field of traditional Chinese medicine and relates to a compound Chinese medicine preparation, in particular to a traditional Chinese medicine composition for treating polycystic kidney disease and a preparation method thereof. Background technique: [0002] Polycystic kidney disease (PKD) is one of the most common hereditary kidney diseases in humans. Its incidence in the world is about 1 / 1000-1 / 400. The main pathological feature is the extensive formation of cysts in both kidneys. Sexual growth, eventually destroying the structure and function of the kidney, and can involve the liver, cardiovascular and many other organs. The age of onset is generally 30-40 years old, and more than 50% of patients aged 60 years enter end-stage renal failure, accounting for about 10% of the causes of end-stage renal failure. About 2.7% of hemodialysis patients are caused by ADPKD (autosomal dominant polycystic kidney disease), and about 3...

Claims

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Application Information

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IPC IPC(8): A61K36/902A61P13/12A61K35/36
Inventor 高建东郑平东何立群王琛侯卫国李瑞玲
Owner SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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