Temperature-and-illumination-controllable type retinal photo-injury quantitative research device

Abstract

The invention relates to a retinal photo-injury quantitative research device, in particular to a temperature-and-illumination-controllable type retinal photo-injury quantitative research device. The research device comprises a camera obscura, a light-emitting diode (LED) face light source, a light source driving unit, a semiconductor refrigeration sheet, a refrigeration sheet driving unit, a photo-sensor, a temperature sensor and a control unit. The light source driving unit drives the LED face light source, the refrigeration sheet driving unit drives the semiconductor refrigeration sheet, the LED face light source is arranged in the camera obscura, and the semiconductor refrigeration sheet, the photo-sensor and the temperature sensor are arranged in a test area. By means of the face light source, the semiconductor refrigeration sheet, the photo-sensor, the temperature sensor and a control unit with a single chip mirco-processor serving as a core, the research device can adjust and control a light strength and temperature device in a sealed space, achieves double control and quantitative monitoring of light strength and temperature, and is fast in reaction, stable in result, high in precision and particularly suitable for photo-injury test research at an isolated cell level.

Description

technical field [0001] The invention relates to a quantitative research device for retinal optical damage, in particular to a temperature and light controllable quantitative research device for retinal optical damage. Background technique [0002] Photodamage, which is damage to the retina caused by too bright light or looking directly at a light source for a long time. The instrument used in the quantitative or qualitative research of retinal cell photodamage is called photodamage research device. The photodamage research device usually includes a confined space, a luminous body and a light intensity control device, etc., by adjusting the brightness of the luminous body, cells or experimental animals in the confined space are given short-term, intense light to achieve the purpose of photodamage. However, at present, in terms of experimental research on photodamage, there is no unified and stable experimental equipment at home and abroad to control the temperature and light...

AI Technical Summary

Problems solved by technology

Due to its inherent limitations, traditional point light sources are difficult to achieve uniform light intensity, and there are problems such as difficult to realize digital control and real-time monitoring. In some occasions, it has been unable to meet the experimental needs of light damage research.

For example, in the related light damage research published by Feng M et al. on pages 151-157 of Int J Ophthalmol published in 2012 and Ueki Y et al. on page e38690 of PLoS One published in 2012, one or more certain wavelengths are placed inside the darkroom. The research on photodamage experiments is carried out in the way of fluorescent lamps, which cannot guarantee the uniformity of light received by the cells in the experiment, and cannot formulate a unified and credible standard for the evaluation of the experiment.

Moreover, in the optical damage research device, temperature, as an important variable in the research of optical damage, has been neglected in a considerable part of the research of domestic and foreign scholars, which may lead to a great reduction in the stability and repeatability of the experiment.

Images