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Positron emitter irradiation system

A radiation system, particle technology, applied in the field of ion beam radiation, can solve the problems of dispersion, difficulty in precise correspondence, high background level, etc.

Inactive Publication Date: 2013-07-24
RADINOVA
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, background levels are high, and in different patient classes the Bragg peak is usually difficult to pinpoint with most PET cameras
Also, because the transient transfer from the input particle to the nuclei in the tissue is small and negligible, the activity due to the target fragmentation reaction can only be used to assess the position of the peak range of the ion beam.
Therefore, this method presents difficulties in establishing an exact correspondence between dose delivery and resulting activity, since the signal is low and the original activity is physically disused and more diffuse

Method used

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Embodiment Construction

[0033] The present invention relates generally to producing 11 C positron emission device and method, especially related to 12 C ion beam generation 11 C positron emits ions.

[0034] Here, for high energy 11 The study of the best choice of decelerating materials produced by maximizing positron emission ions is the introduction of low emission 12 C ion beam interaction. Here we studied based on relative flow and average energy 11 The quantity and quality of the C radiation beam, the relative flow rate and the average energy are a function of the decelerating material and its thickness and the remaining energy when exiting the decelerator.

[0035] Fragment generation

[0036] When a photoion beam penetrates a thick target, it undergoes a nuclear reaction with the target atom, and its slowing down process is affected by nuclear fragmentation reactions, which cause the attenuation of the incoming beam and establish a variety of primary beams and target-like fragments. In the energy r...

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Abstract

Analysis of the production of 11C fragments mainly by projectile fragmentation of a stable monodirectional and monoenergetic primary 12C beam in different decelerating materials are presented and the optimal target choice have been identified to obtain the highest possible beam quality of decelerated 11C beam at arbitrary energies and therapeutic ranges. The optimal 11C-generating target is made of hydrogen preferably followed by a digitally variable decelerator of a hydrogen rich compound, such as polyethylene, to maximize the quality of the 11C beam.

Description

Technical field [0001] The embodiments of the present invention generally relate to ion beam radiation, and particularly relate to the generation of positron-emitting radiation beams, which are useful for ion radiation therapy to increase their visibility in PET and PET-CT imaging. Background technique [0002] Accurate monitoring of the dose and response of tumors and surrounding normal tissues is a key issue for external radiotherapy. For photoion therapy, this is particularly important because their sharp depth dose distribution and steep lateral beam profile should be precisely positioned to make their high physical and bioselective applications ideal and normal tissue The morbidity is minimized. The high energy density released at the end of the particle range produces a sharp dose, with the maximum at the Bragg peak, which is important for positioning within the target volume of the patient. In photoion therapy, it is particularly important to use ions heavier than hydrog...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G21G1/00A61N5/10G21G4/08G21K5/00
CPCA61N5/1071G21G1/10G21G4/08A61N5/10A61N5/1048A61N2005/1087A61N2005/1052A61N2005/1095
Inventor 安德斯·巴哈姆玛塔·拉泽罗尼
Owner RADINOVA