Traditional Chinese medicine composition for treating simple obesity, and preparation method and application thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treating simple obesity, and a preparation method and an application thereof. The traditional Chinese medicine composition is prepared by using 5-30 parts by mass of white atractylodes rhizome, 10-30 parts by mass of fried turtle shell, 10-20 parts by mass of inula flowers, 10-20 parts by mass of curcuma zedoary and 10-20 parts by mass of giant knotweed rhizome as raw materials. Specifically, the preparation method comprises the following steps of weighing all medicines according to the above proportions; smashing the fried turtle shell; adding water 10 times by volume that of the fried turtle shell; decocting for 30 minutes; adding traditional Chinese medicinal materials; adding water and decocting for two times, wherein the volume of added water in each time is 8-10 times that of a total mass of the medicines; and the time for each decoction is 0.5-1 hour; merging extract solutions obtained by the two times of decoction; filtering, concentrating, and drying to obtain a dry extract. Animal experiments show that the composition can significantly reduce body weight, liver weight and fat weight of high-fat obese rats, significantly reduce the contents of liver cholesterol and liver triglyceride in the high-fat obese rats, regulate lipid metabolism and improve liver functions. The medicine effects are related to the fact that the composition can increase bile flow, regulate and increase bile acid subfractions that can promote bile secretion and the lipid metabolism.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating simple obesity, a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. Background technique [0002] Obesity and its closely related hyperlipidemia, diabetes, cardiovascular disease and cancer have become global medical and social problems. WHO defines obesity as a serious chronic metabolic disease. Among them, simple obesity accounts for more than 90%. Western medicine currently treats obesity mainly with appetite suppressants, drugs that affect digestion and absorption, and hormone drugs that accelerate metabolism. However, severe side effects such as steatosis and subcutaneous fat mound, liver function damage, dependence and rebound are common. At present, the traditional Chinese medicine understanding of obesity is mostly based on the ancients' elaboration on the aspects of "ointment", "fat man" and "meat ma...

AI Technical Summary

Problems solved by technology

However, the existing problems of traditional Chinese medicine in this field are: failure to theoretically clarify the TCM category of obesity; one-sided emphasis on the application and role of a single treatment method in weight loss, and failure to fundamentally regulate the whole body and improve the body's health. Metabolic function; although the lipid-lowering and weight-loss prescriptions used in clinical practice are effective, they often need to be combined with "diet" and "extensive exercise"; often have side effects such as diarrhea and fatigue

This not only affects the quality of life of patients, makes the curative effect difficult to last, but also tends to rebound after stopping treatment

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