Preparation method of high-purity silk fibroin peptide

A high-purity, silk fibroin peptide technology, which is applied in the preparation method of peptides, chemical instruments and methods, peptides, etc., can solve the problems of low purity and achieve the effects of short process time, good application prospects, and simple preparation methods
CN103243145AInactive Publication Date: 2013-08-14SUZHOU UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SUZHOU UNIV
Publication Date
2013-08-14
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a preparation method of high-purity silk fibroin peptide. The preparation method comprises the following steps of: (1) degumming and refining damaged cocoon or bavella silk serving as a raw material by using an Na2CO3 solution, and then washing and drying to obtain silk fibroin; (2) dissolving the silk fibroin by using a CaCl2-H2O-C2H5OH ternary system; (3) diluting, and then carrying out enzymolysis by using neutral proteinase; (4) filtering by adopting electrodialysis; (5) filtering by adopting dislysis; and (6) concentrating, carrying out spray drying, and sterilizing to obtain the high-purity silk fibroin peptide. According to the preparation method, tests prove that the desalinization ratio is 99.5%, and the content of peptide in a finally obtained silk fibroin peptide product is more than 94% and meets the use requirements of pharmaceuticals, cosmetics, medical materials, and the like, so that the problem of the field is solved, and the creativity is achieved.
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Description

technical field

[0001] The invention relates to a preparation method of high-purity silk fibroin peptide. Background technique

[0002] At present, silk fibroin peptide is an advanced raw material for advanced natural nutritional skin care and hair care products. Adding silk fibroin peptide to skin care products can increase the vitality of skin cells and have the effect of sunscreen, whitening and moisturizing; adding silk peptide to hair care products , can form a protective film on the surface of the hair, increase the elasticity of the hair, nourish and moisturize, and can repair the damage caused by perm and hair dyeing. In addition, silk fibroin peptide also has important utilization value in biopharmaceuticals, external medical materials and functional health food, and can be made into liver-protecting drugs, diabetes drugs, Alzheimer's drugs, etc.; it can be applied It is used in the manufacture of medical supplies such as contact lenses, artificial skin and wound m...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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